DRSC/TRiP Functional Genomics Resources

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Protein Alignment Cyp309a2 and Tbxas1

DIOPT Version :9

Sequence 1:NP_608689.2 Gene:Cyp309a2 / 33439 FlyBaseID:FBgn0041337 Length:538 Species:Drosophila melanogaster
Sequence 2:NP_035669.3 Gene:Tbxas1 / 21391 MGIID:98497 Length:533 Species:Mus musculus


Alignment Length:534 Identity:124/534 - (23%)
Similarity:215/534 - (40%) Gaps:95/534 - (17%)


- Green bases have known domain annotations that are detailed below.


  Fly    40 LILLHLLVLPIYLYLTWH----HKYWRKRGLVTARPLTLLGTYPGLLTRKSNLVFDVQKIYD-KY 99
            ::.:.|||..:.| |.|:    .....|.|:...:|...:|          ||:|..|..:: :.
Mouse    15 IVTVTLLVALLAL-LKWYSMSAFSRLEKLGIRHPKPSPFVG----------NLMFFRQGFWESQL 68

  Fly   100 KGKHR---AVGVFVTRQPQILVLDPELAHEVLVSNFRCYKDSLQSSYLRHAKWDKYARLNPFWAS 161
            :.:.|   ..|.::.|:..:::.:|::..:|||.||..:.:.:.|........|....|.     
Mouse    69 ELRERYGPLCGYYLGRRMHVVISEPDMIKQVLVENFSNFSNRMASGLEPKMVADSVLLLR----- 128

  Fly   162 GQSWRRLRTDAQAGISGSRLRQAYNIWEQGGQMLTEYMTQQVAEKNNILETRDLCFRYTAHVMAD 226
            .:.|..:|....:..|..:|.:...:..|..::|..::.:..|.::.....|..|. ||..|:|.
Mouse   129 DRRWEEVRGALMSSFSPEKLDEMTPLISQACELLVAHLKRYAASRDAFNIQRCYCC-YTIDVVAS 192

  Fly   227 FIWGIDAGTLTRPMEQP--NKVQEMASKWTSYAFYMLTLFMATIVAPCSRLLLRFRFYPKETDE- 288
            ..:|....:...| |.|  ...:..::........:|.|...:|:.|.:|:|..     |..|| 
Mouse   193 VAFGTQVDSQNSP-EDPFVQHCRRASTFCIPRPLLVLILSFPSIMVPLARILPN-----KNRDEL 251

  Fly   289 --FFSNLTKESIELR-LKAGDSTRTDYLSHLLQLR------------------------------ 320
              ||:.|.:..|.|| .:|.:..|.|:|..:|..:                              
Mouse   252 NGFFNTLIRNVIALRDQQAAEERRRDFLQMVLDAQHSMNSVGVEGFDMVPESLSSSECTKEPPQR 316

  Fly   321 -----DQKQATHDDLVGHALTVMLDGYDTSGTALLHALYYLAENPAVQQKLRVEILSCMASEKSL 380
                 ..|..|.|::||.|...::.|::.....|....|.||.:|..|::|..|:...|....:.
Mouse   317 CHPTSTSKPFTVDEIVGQAFLFLIAGHEVITNTLSFITYLLATHPDCQERLLKEVDLFMGKHPAP 381

  Fly   381 DFEKL-SSLQYLEQVIYESLRLSSLIPQYTKVCTLPTVIRLSESKSLDVEV-------GMTIMIP 437
            ::..| ..|.||:.||.|:||:            .|...|.:...:.|.||       |..:.|.
Mouse   382 EYHSLQEGLPYLDMVISETLRM------------YPPAFRFTREAAQDCEVLGQRIPAGTVLEIA 434

  Fly   438 NYQFHHDKQYFPEPEAFKPERFDNGAYQELMRKGI-FLPFSDGPRICMGVPLAMLTLKSALVHIL 501
            ....|||.:::|.||.|.||||.  |...|.|:.. :|||..|||.|:||.|.:|.:|..::.:|
Mouse   435 VGALHHDPEHWPNPETFDPERFT--AEARLQRRPFTYLPFGAGPRSCLGVRLGLLVVKLTILQVL 497

  Fly   502 SNFQVVRGRDRLIP 515
            ..|:.....:..:|
Mouse   498 HKFRFEASPETQVP 511

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Cyp309a2NP_608689.2 p450 70..526 CDD:299894 116/500 (23%)
Tbxas1NP_035669.3 p450 47..528 CDD:365848 116/501 (23%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG0158
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D264519at33208
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
32.820

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