Protein Alignment Cyp309a2 and Cyp4f17

DIOPT Version :10

• Sequence 1: NP_608689.2
• Gene: Cyp309a2 / 33439
• FlyBaseID: FBgn0041337
• Length: 538
• Species: Drosophila melanogaster
• Sequence 2: NP_001094915.1
• Gene: Cyp4f17 / 208285
• MGIID: 3646233
• Length: 524
• Species: Mus musculus
• Alignment Length: 557
• Identity: 128/557 - (22%)
• Similarity: 221/557 - (39%)
• Gaps: 144/557 - (25%)

  Fly    42 LLHLLVLPIYL--YLTW-------------------HHKYWRKRGLVTARPLTLLGTYPGLLTRK 85
            ||.|:...::|  .|||                   .|.:|....:|......|     .|||.:
Mouse    21 LLQLVGASLFLARILTWICAFYDNYCRLRCFPEPPSRHWFWGHMSMVKNNEEGL-----QLLTER 80

  Fly    86 SNLVFDVQKIYDKYKGKHRAVGVFVTRQPQILVLDPELAHEVLVSNFRCYKDSLQSSYLRHAKWD 150
            |:...||...:         :|.|   .|.:.::.|:....:|.:          |:.:...:..
Mouse    81 SHQFHDVHLCW---------IGPF---YPILRLIHPKFIGPILQA----------SAAVAPKEMI 123

  Fly   151 KYARLNPFW-------ASGQSWRRLRTDAQAGISGSRLRQAYNIWEQGGQMLTEYMTQQVAEKN- 207
            .|..|.| |       ::|:.|.|.|         ..|..|::.     .:|..||      ||
Mouse   124 FYGFLKP-WLGDGLLVSAGEKWSRHR---------HLLTPAFHF-----DILKPYM------KNF 167

  Fly   208 ----NILETR--------DLCFRYTAHV-------MADFIWGIDAGTLTRPMEQPNKVQEMAS-- 251
                ||:..:        ..|.....|:       :.:.::..|:.....|.|....:||::|
Mouse   168 NKSVNIMHAKWQRLTTKGTACLDMLEHISLMTLDSLQNCVFSFDSNCQESPSEYIAAIQELSSLI 232

  Fly   252 --------KWTSYAFYMLTLFMATIVAPCSRLLLRFR--------FYPKETDEFFSNLTKESIEL 300
                    .:..:.:|            |:....|||        |......|....|:.::::.
Mouse   233 VKRHHQPFLYLDFLYY------------CTADGRRFRKACDLVHNFTDAVIRERRRTLSSQNLDE 285

  Fly   301 RLKAGDSTRT-DYLSHLLQLRDQ--KQATHDDLVGHALTVMLDGYDTSGTALLHALYYLAENPAV 362
            .||:...::| |::..||..:|:  |:.:.:|:...|.|.|..|:||:.:||...||.||.:|..
Mouse   286 FLKSKTKSKTLDFIDVLLLAKDEHGKELSDEDIRAEADTFMFGGHDTTASALSWILYNLARHPEY 350

  Fly   363 QQKLRVEILSCMASE--KSLDFEKLSSLQYLEQVIYESLRLSSLIPQYTKVCTLPTVIRLSESKS 425
            |::.|.|:...:...  :.::::.|:.|.:|...|.|||||...:...::.||...|  |.:.:.
Mouse   351 QERCRQEVQELLRGREPQEIEWDDLAQLPFLTMCIKESLRLHPPVTVISRCCTQDVV--LPDGRV 413

  Fly   426 LDVEVGMTIMIPNYQFHHDKQYFPEPEAFKPERFDNGAYQELMRKGI-FLPFSDGPRICMGVPLA 489
              :..|...:|..:..||:.:.:|:||.:.|.|||....|:  |..: |:|||.|||.|:|...|
Mouse   414 --IPKGTDCVISIFGVHHNPEVWPDPEVYDPFRFDPENPQK--RSPLAFIPFSAGPRNCIGQTFA 474

  Fly   490 MLTLKSALVHILSNFQVVRG------RDRLIPKGDSG 520
            |..:|.||...|..|:|:.|      :..||.:.:.|
Mouse   475 MREMKVALALTLLRFRVLPGDKEPRRKPELILRAEGG 511

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp309a2	NP_608689.2	CYP6-like	101..526	CDD:410679	111/477 (23%)
Cyp4f17	NP_001094915.1	CYP4F	74..515	CDD:410772	118/504 (23%)