Protein Alignment Cyp309a2 and cyp-13A3

DIOPT Version :10

• Sequence 1: NP_608689.2
• Gene: Cyp309a2 / 33439
• FlyBaseID: FBgn0041337
• Length: 538
• Species: Drosophila melanogaster
• Sequence 2: NP_496110.1
• Gene: cyp-13A3 / 188359
• WormBaseID: WBGene00011675
• Length: 520
• Species: Caenorhabditis elegans
• Alignment Length: 557
• Identity: 139/557 - (24%)
• Similarity: 243/557 - (43%)
• Gaps: 102/557 - (18%)

  Fly    37 SLALILLHLLVLPIYLYLTWHHKYWRKRGLVTARPLTLLGTYPGLLTRKSNLVF---DVQKIYDK 98
            ||::::...|.:.::.|..|...:|.::|:...|.|...|......:.:...:.   |..|.|..
 Worm     2 SLSILIAIALFIGVFTYYLWIWSFWMRKGIKGPRGLPFFGIINAFQSYEKPWILRLGDWTKEYGP 66

  Fly    99 YKGKHRAVGVFVTRQPQILVLDPELAHEVLVSNFRCY----KDSLQSSYLRHAKWDKYARLNPFW 159
            ..|....|      :..::|.|||..|||.|..|..:    ::.||...      ||..|::...
 Worm    67 MYGFTDGV------EKTLVVSDPEFVHEVFVKQFDNFYARKQNPLQGDP------DKDPRIHLVT 119

  Fly   160 ASGQSWRRLRTDAQAGISGSRLRQAYNIWEQGGQMLTEYMTQQVAEKNNILE-------TRDLCF 217
            :.|..|:||||.|....|...||:.::..|           :.|||....||       |.|:..
 Worm   120 SQGHRWKRLRTLASPTFSNKSLRKIFSTVE-----------ESVAEMMRHLEKGTAGGKTIDILE 173

  Fly   218 RYTAHVMADFIWGIDAGTLTRPM-EQP--NKVQEMASKWTSYAFYMLTLFMATIVAPCSRLLLRF 279
            .|....| |.|..|..|.....| |.|  :|::.:.:...:      .:|:...:.|.:..:.|:
 Worm   174 YYQEFTM-DIIGKIAMGQSGSMMFENPWLDKIRAIFNTRGN------IIFIICGIVPFTGSIFRW 231

  Fly   280 RFYPKETDEFFSNLTKESIELRL-----------KAGDSTR----------------TDYL---- 313
            .|....|.:..::| ..::|:.|           |||..:.                ||:|
 Worm   232 FFSKVPTAQTVTSL-MHTLEIALTKRVEQRAADEKAGIESSGEPQDFIDLFLDVQADTDFLEDET 295

  Fly   314 ------SHLLQLRDQKQATHDDLVGHALTVMLDGYDTSGTALLHALYYLAENPAVQQKLRVEI-L 371
                  |.::::  .|..|.|:::|.....:|.||||:..:|.::.|.||.:|.:|:||:.|: .
 Worm   296 KNGFARSQIVKV--DKHLTFDEIIGQLFVFLLAGYDTTALSLSYSSYLLARHPEIQKKLQEEVDR 358

  Fly   372 SCMASEKSLDFEKLSSLQYLEQVIYESLR---LSSLIPQYTKVCTLPTVIRLSESKSLDVEVGMT 433
            .|  .:..:.|::||.|:|:|.||.|:||   |:|::  :.:.|...|.:     ..:.:|.|..
 Worm   359 EC--PDPEVTFDQLSKLKYMECVIKETLRLYPLASIV--HNRKCMKSTTV-----LGMKIEEGTN 414

  Fly   434 IMIPNYQFHHDKQYFPE-PEAFKPERFDNGAYQELMRKGIFLPFSDGPRICMGVPLAMLTLKSAL 497
            :....:..|:|.:::.| ...|||||:::|. ::.:.||.:|||..|||||:|:.||.:..|..|
 Worm   415 VQADTWTLHYDPKFWGENANEFKPERWESGD-EQAVAKGAYLPFGLGPRICIGMRLAYMEEKMLL 478

  Fly   498 VHILSNFQVVRGRDRLIPKGDSGFGVVLQGDVNLEYR 534
            ..||..:.:....:..||....|.......:|:|:.:
 Worm   479 AQILKKYSLETTFETHIPLKLVGIATTAPTNVHLKLK 515

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp309a2	NP_608689.2	CYP6-like	101..526	CDD:410679	124/480 (26%)
cyp-13A3	NP_496110.1	CYP3A-like	63..509	CDD:410678	125/488 (26%)