Protein Alignment Cyp309a2 and cyp-13A8

DIOPT Version :10

• Sequence 1: NP_608689.2
• Gene: Cyp309a2 / 33439
• FlyBaseID: FBgn0041337
• Length: 538
• Species: Drosophila melanogaster
• Sequence 2: NP_496115.1
• Gene: cyp-13A8 / 188358
• WormBaseID: WBGene00011674
• Length: 509
• Species: Caenorhabditis elegans
• Alignment Length: 509
• Identity: 125/509 - (24%)
• Similarity: 213/509 - (41%)
• Gaps: 78/509 - (15%)

  Fly    41 ILLHLLVLPIYLYLTWHHKYWRKRGLVTARPLTLLGTYPGLLTRKSNLVFDVQKIYDKYKGKHRA 105
            ::..|:::.|..|..||..:|::|||.....:.:.|....:|.......:.:|| :.|..||  .
 Worm     1 MIFELILISIVTYYFWHWTFWKRRGLPGPWGVPIFGKAGAMLEDSFPPGYTLQK-WTKEYGK--I 62

  Fly   106 VGVFVTRQPQILVLDPELAHEVLVSNFRCYKDSLQSSYLR-----HAKWDKYARLNPFWASGQSW 165
            .|.....|..:::.||:|..|:||..:       .:.|.|     ....||...::...|.|..|
 Worm    63 YGFTEGMQKVMVISDPDLVQEILVKQY-------DNFYGRKHNPVQGDPDKDKDIHIVGAQGFRW 120

  Fly   166 RRLRTDAQAGISGSRLRQAYNIWEQGGQMLTEYMTQQVAEKNNILETRDLCFRYTAHVMADFIWG 230
            :||||......|...:::.....|...|.|.:.:.:: :|....:........||..|::....|
 Worm   121 KRLRTITAPAFSNGSIKKVLTTMEDSTQELMKKLREE-SENGKAVNMHLFYQEYTFDVISRVAMG 184

  Fly   231 -IDAGTLTRPMEQPNKVQEMASKWTSYAF---------YMLTLFMAT--------IVAPCSRLLL 277
             .|:.....|:.:..|.....::|..:.|         ::..||:..        ||...|
 Worm   185 QPDSQMFKNPLLKDVKGFFEHNRWQIWMFSGGFPFAVSFLKWLFIKVGKFGAGPFIVVQKS---- 245

  Fly   278 RFRFYPKETDEFFSNLTKESIELRLKAGDSTRTDYLSHLLQLR-------------------DQK 323
                   .||...|.:.:...:.:.........||:...|..|                   :.:
 Worm   246 -------VTDAVMSRIAQREADKKHGVEPGEAADYIDMFLNARAEVEHFGESNDEFHKSSSYNNR 303

  Fly   324 QATHDDLVGHALTVMLDGYDTSGTALLHALYYLAENPAVQQKLRVEI-LSCMASEKSLDFEKLSS 387
            |.|..:::......::.|:||:..:|.:..|:||.||.:|.||:.|: ..|...|  :.|::||.
 Worm   304 QLTTQEIISQCFVFLVAGFDTTAISLSYVTYFLALNPKIQSKLQDEVDKECPNDE--ITFDQLSK 366

  Fly   388 LQYLEQVIYESLRLSSLIP-QYTKVCTLPTVIRLSESKSLDVEVGMTIMIPNYQFHHDKQYF-PE 450
            |:|::.||.|||||..... ..::.|...|||    .:.: ||.|:.:||..:..||||..: .:
 Worm   367 LKYMDNVIKESLRLFPFASFANSRRCMRNTVI----GEQI-VEAGVDVMIDTWTLHHDKNVWGND 426

  Fly   451 PEAFKPERFDNGAYQELMRKGIFLPFSDGPRICMGVPLAMLTLKSALVHILSNF 504
            .|.|||||:|:    .|..:..:|.|..|||:|:|:..|:|..|..|.|||..:
 Worm   427 VEEFKPERWDS----PLTPQQAYLSFGAGPRVCLGMRFALLEQKGLLSHILKKY 476

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp309a2	NP_608689.2	CYP6-like	101..526	CDD:410679	111/449 (25%)
cyp-13A8	NP_496115.1	CYP3A-like	58..500	CDD:410678	111/451 (25%)