Protein Alignment Cyp309a2 and cyp-13A12

DIOPT Version :10

• Sequence 1: NP_608689.2
• Gene: Cyp309a2 / 33439
• FlyBaseID: FBgn0041337
• Length: 538
• Species: Drosophila melanogaster
• Sequence 2: NP_499705.1
• Gene: cyp-13A12 / 184473
• WormBaseID: WBGene00008810
• Length: 518
• Species: Caenorhabditis elegans
• Alignment Length: 511
• Identity: 131/511 - (25%)
• Similarity: 230/511 - (45%)
• Gaps: 72/511 - (14%)

  Fly    38 LALILLHLL-----VLPIYLYLTWHHKYWRKRGLVTARPLTLLGTYPGLLTRKSNLVFDVQKIYD 97
            :|:|.|.:|     ||..||: ||  .||::||:.......:||:...:|: ..|..:...|.:.
 Worm     1 MAIIFLAILTSIIGVLSFYLW-TW--SYWKRRGIAGPSGYPILGSALEMLS-SENPPYLQLKEWT 61

  Fly    98 KYKGKHRAVGVFVTRQPQILVLDPELAHEVLVSNFRCYKDSLQSSYLRHAKWD--KYARLNPFWA 160
            |..||  ..|:.......:::.||:|..||.|..:    |:.....|...:.|  |..|:|.|.:
 Worm    62 KQYGK--VYGITEGLSRTLVISDPDLVQEVFVKQY----DNFFGRKLNPIQGDPNKDKRVNLFSS 120

  Fly   161 SGQSWRRLRTDAQAGISGSRLRQAYNIWEQGGQMLTEYMTQQVAEKNNILETRDLCFRYTAHVMA 225
            .|..|:||||.:....|.:.||:.....|:....|..:: :|..:....::..|....:|..|:.
 Worm   121 QGHRWKRLRTISSPTFSNNSLRKLKTTVEECAVELLRHI-EQHTDGGQPIDLLDFYQEFTLDVIG 184

  Fly   226 DFIWG-IDAGTLTRPM--------EQPNK---VQEMASKWTSYAFYMLTLFMATIVAPCSRLLLR 278
            ....| .|:.....|:        .:|.|   :....:.|......|:...:..||...:..::|
 Worm   185 RIAMGQTDSQMFKNPLLPYVRAVFGEPRKGLFLSGSLAPWIGPILRMVMFSLPNIVKNPAVHVIR 249

  Fly   279 FRFYPKETDEFFSNLTKESIELRL---KAG--DSTRTDYLSHLLQLRDQ---------------- 322
            ..          ||..::.::||:   |||  .....|::...|..:..
 Worm   250 HT----------SNAVEQRVKLRMADEKAGIDPGEPQDFIDLFLDAKSDDVELENNEDFTKAGVK 304

  Fly   323 --KQATHDDLVGHALTVMLDGYDTSGTALLHALYYLAENPAVQQKLRVEI-LSCMASEKSLDFEK 384
              :|.|.:::||.....::.|:||:..:|.::.:.||.:|.||:||:.|| ..|  ::..:.|::
 Worm   305 VTRQLTTEEIVGQCFVFLIAGFDTTALSLSYSSFLLATHPKVQKKLQEEIDREC--ADPEVTFDQ 367

  Fly   385 LSSLQYLEQVIYESLRLSSLIPQYTKVCTLPTVIRLSESKSLDVEVGMTIMIPNYQFHHDKQYFP 449
            ||.|:|:|.||.|:||:..|.......|.:    |.::..:.:::.|..|:...:..|.||..:.
 Worm   368 LSKLKYMECVIKETLRMYPLGALANSRCCM----RATKIGNYEIDEGTNILCDTWTLHSDKSIWG 428

  Fly   450 E-PEAFKPERFDNGAYQELMRKGIFLPFSDGPRICMGVPLAMLTLKSALVHILSNF 504
            | .|.|||||:::|. :...:||.::||..|||.|:|:.||.:..|..|.|||..:
 Worm   429 EDAEEFKPERWESGD-EHFYQKGGYIPFGLGPRQCIGMRLAYMEEKLLLSHILRKY 483

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp309a2	NP_608689.2	CYP6-like	101..526	CDD:410679	111/443 (25%)
cyp-13A12	NP_499705.1	CYP3A-like	63..507	CDD:410678	111/445 (25%)