Protein Alignment Cyp309a2 and Cyp3a11

DIOPT Version :10

• Sequence 1: NP_608689.2
• Gene: Cyp309a2 / 33439
• FlyBaseID: FBgn0041337
• Length: 538
• Species: Drosophila melanogaster
• Sequence 2: NP_031844.1
• Gene: Cyp3a11 / 13112
• MGIID: 88609
• Length: 504
• Species: Mus musculus
• Alignment Length: 525
• Identity: 147/525 - (28%)
• Similarity: 251/525 - (47%)
• Gaps: 91/525 - (17%)

  Fly    32 MYILASLAL---ILLHLLVLPIYLYLTWHHKYWRKRGLVTARPLTLLGT----YPGLLTRKSNLV 89
            |.::::|:|   :||.:.::.:|.|.|..|:.::|:|:...:||..|||    |.||..
Mouse     1 MDLVSALSLETWVLLAISLVLLYRYGTRKHELFKKQGIPGPKPLPFLGTVLNYYKGLWK------ 59

  Fly    90 FDVQKIYDKYKGKHRAVGVFVTRQPQILVLDPELAHEVLV----SNFRCYKD-------SLQSSY 143
            ||:: .|.|| ||  ..|:|..:.|.:.|.|||....|||    |.|...:|       |...|.
Mouse    60 FDME-CYKKY-GK--TWGLFDGQTPLLAVTDPETIKNVLVKECFSVFTNRRDFGPVGIMSKAISI 120

  Fly   144 LRHAKWDKY-ARLNPFWASGQSWRRLRTDAQAGISGSRLRQAYNIWEQGGQMLTEYMTQQVAEKN 207
            .:..:|.:| |.|:|.:.||                 :|::.:.:.||.|.:|.:|:.|: |:|.
Mouse   121 SKDDEWKRYRALLSPTFTSG-----------------KLKEMFPVIEQYGDILVKYLRQK-AKKG 167

  Fly   208 NILETRDLCFRYTAHVMADFIWGIDAGTLTRPMEQPNKVQEMASKWTSYAFYMLTLFMATI---V 269
            ..:..:|:...|:..|:....:|::..:|..| |.|  ..|.|.|...:.|:...||...:   :
Mouse   168 KPVTMKDVLGAYSMDVITSTSFGVNVDSLNNP-EDP--FVEKAKKLLRFDFFDPLLFSVVLFPFL 229

  Fly   270 APCSRLLLRFRFYPKETDEFFSNLTKESIELRLKAGDSTRTDYLSHLLQLRD-------QKQATH 327
            .|... :|....:||::.|||........|.||.:....|.|:|..::...:       .|..:.
Mouse   230 TPVYE-MLNICMFPKDSIEFFKKFVDRMKESRLDSKQKHRVDFLQLMMNSHNNSKDKVSHKALSD 293

  Fly   328 DDLVGHALTVMLDGYDTSGTALLHALYYLAENPAVQQKLRVEILSCMASEKSLDFEKLSSLQYLE 392
            .::...::..:..||:|:.:.|...|:.||.:|.:|:||:.||...:.::....::.:..::||:
Mouse   294 MEITAQSIIFIFAGYETTSSTLSFTLHSLATHPDIQKKLQDEIDEALPNKAPPTYDTVMEMEYLD 358

  Fly   393 QVIYESLRLSSLIPQYTKVCTLPTVIRLSESKSLDVEV-------GMTIMIPNYQFHHDKQYFPE 450
            .|:.|:|||..:..:..:||            ..|||:       |.|:|||:|..|||.|::.|
Mouse   359 MVLNETLRLYPIANRLERVC------------KKDVELNGVYIPKGSTVMIPSYALHHDPQHWSE 411

  Fly   451 PEAFKPERFDNGAYQELMRKG-----IFLPFSDGPRICMGVPLAMLTLKSALVHILSNFQVVRGR 510
            ||.|:||||..      ..||     ::|||.:|||.|:|:..|::.:|.||..|:.||.....:
Mouse   412 PEEFQPERFSK------ENKGSIDPYVYLPFGNGPRNCLGMRFALMNMKLALTKIMQNFSFQPCK 470

  Fly   511 DRLIP 515
            :..||
Mouse   471 ETQIP 475

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp309a2	NP_608689.2	CYP6-like	101..526	CDD:410679	123/449 (27%)
Cyp3a11	NP_031844.1	CYP3A	67..493	CDD:410743	125/452 (28%)