DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp309a1 and CYP705A8

DIOPT Version :9

Sequence 1:	NP_001259943.1	Gene:	Cyp309a1 / 33438	FlyBaseID:	FBgn0031432	Length:	506	Species:	Drosophila melanogaster
Sequence 2:	NP_180268.1	Gene:	CYP705A8 / 817242	AraportID:	AT2G27000	Length:	514	Species:	Arabidopsis thaliana

Alignment Length:	500	Identity:	116/500 - (23%)
Similarity:	197/500 - (39%)	Gaps:	86/500 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 CLTIVHVAFAVVYFYLTWYHKYWDKRGVVTAEP-LTILGSYPGIL-INKSRSLILDVQDVYNKYK 70
            ||.::.:....:..|..::.|..|...:..:.| |.|:|....:| :...|||        .|..
plant    12 CLILILLCLLSILCYSFFFKKPKDGFNLPPSPPSLPIIGHLHHLLSLFMHRSL--------QKLS 68

  Fly    71 DKY-RTVGTFITRQPQLLVLDPALAHEIL--VDKFSHFRDTITSSFVGHNPDDKYVAGSPFFSA- 131
            .|| ..:...:...|.|||..|::|:||.  .|.....||..|      |....::....|.:|
plant    69 SKYGPLLYLHVFNVPILLVSSPSIAYEIFRAQDVNVSTRDFPT------NEGSLFLGSFSFITAP 127

  Fly   132 -GDKWKRLRSENVGGLT-PSRLKMAYSIWEQSGRKLVEYIER--------ARREQGDIIETRDLA 186
             |:.||.::...|..|. |..|       |:|.|.....:||        |.:::.  :|..|.|
plant   128 YGEYWKFMKKLIVTKLLGPQAL-------ERSQRIRANEVERFYSNLLDKAMKKES--VEIADEA 183

  Fly   187 YRFTANAMADFIWGIDAGSLSGKVGEI-GDFQKTSTDWSAHAFSSMIR--FNKTLVAIFVRKLF- 247
            .:...|.:...|.|......:|:...| |...|:.........::::|  ..|..:.:| :|:|
plant   184 MKLVNNIICKMIMGRTCSEENGEAERIRGLVTKSDALLKKFLLAAILRKPLKKIGITLF-KKVFM 247

  Fly   248 --SMRFFTKATDEFFLR-LTQDAVNLRQGGSGEGRTDYLSHLIQLQ-QRGNSIHDSVGHALTVHL 308
              |::|     ||...: |.::...|.:...|   ||.:..|:::. .:.:....:..|..::.:
plant   248 DISLKF-----DEVLEKILVENEERLEENQQG---TDIMDKLLEVYGDKTSEYKITRDHIKSLFV 304

  Fly   309 D----GFETSGAVLYHMLYSLSEHHEEQEKLRSEILEALASEGQISYDQINNLPYLDQCFNESLR 369
            |    |.:|:...:...:..:..:....|:||.||...:.....|....:.||.||.....|.||
plant   305 DLFFAGTDTATHTIEWTMAEIMNNSLILERLREEIDSVVGKTRLIQETDLPNLLYLQATVKEGLR 369

  Fly   370 LTTPIGFFMRI----CTKPTQINLGDDKTLDLEPGVTVMVPAYQYHHDNDIYPEASEFRPDRFEN 430
            |...|...:|.    ||      :|.   ..:.....::|..|....|.|.:.:..||:|:||..
plant   370 LHPTIPLVLRTFQDGCT------IGG---FSIPKKTKLVVNGYAIMRDPDNWEDPLEFKPERFLA 425

  Fly   431 GAAS---------VLTKRGCFLPFGDGPRICLGMRVGQLSVKTAI 466
            .:.|         ||.    :|.||.|.|.|.|:.:..:||:|||
plant   426 SSRSSQKDAIKEEVLK----YLSFGSGRRGCPGVNLAYVSVETAI 466

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp309a1	NP_001259943.1	p450	49..481	CDD:299894	106/457 (23%)
CYP705A8	NP_180268.1	p450	55..506	CDD:299894	106/456 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D467733at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010