Protein Alignment Cyp309a1 and Cyp3a25

DIOPT Version :9

• Sequence 1: NP_001259943.1
• Gene: Cyp309a1 / 33438
• FlyBaseID: FBgn0031432
• Length: 506
• Species: Drosophila melanogaster
• Sequence 2: NP_062766.2
• Gene: Cyp3a25 / 56388
• MGIID: 1930638
• Length: 503
• Species: Mus musculus
• Alignment Length: 508
• Identity: 132/508 - (25%)
• Similarity: 237/508 - (46%)
• Gaps: 77/508 - (15%)

  Fly    10 TIVHVAFAVVYFYL--TWYHKYWDKRGVVTAEPLTILGSYPGILINKSRSLILDVQDVYNKYKDK 72
            |.|.:..::|.||:  |:.|..:.|.|:...:||.:||:    :.|....:....:|.|.||.
Mouse    11 TWVLLVTSLVLFYIYGTYSHGLFKKLGIPGPKPLPLLGT----IFNYYDGMWKFDEDCYKKYG-- 69

  Fly    73 YRTVGTFITRQPQLLVLDPALAHEILVDK-FSHFRDTITSSFVGHNPDDKYVAGSPFFSAGDKWK 136
             :..|.:...||.|.::||.:...:||.: :|.|.:......||      ::..:...|..::||
Mouse    70 -KIWGFYEGPQPILAIMDPEIIKIVLVKECYSVFTNRRFFGPVG------FMKKAITISEDEEWK 127

  Fly   137 RLRSENVGGLTPSRLKMAYSIWEQSGRKLVEYIERARREQGDIIETRDLAYRFTANAMADFIWGI 201
            |||:......|..:||..:.|..|.|..||..:.| ..|:|:.|..:|:...::.:.:....:|:
Mouse   128 RLRTLLSPTFTSGKLKEMFPIMRQYGDILVRNLRR-EEEKGEPISMKDIFGAYSMDVITGTSFGV 191

  Fly   202 DAGSLSG-------KVGEIGDFQKTSTDWSAHAFSSMIRFNKTLVAI----FVRKLFSM---RFF 252
            :..||:.       |..:|..|:               .|:..|::|    |:..::.|   ..|
Mouse   192 NVDSLNNPQDPFVQKAKKILKFK---------------IFDPFLLSIILFPFLTPIYEMLNFSIF 241

  Fly   253 TKATDEFFLRLTQDAVNLRQGGSGEGRTDYLSHLIQLQ-------QRGNSIHDSVGHALTVHLDG 310
            .:.:..||.:..:.....|...:.:.|.|:|..::..|       |:..|..:....|:.....|
Mouse   242 PRDSMNFFKKFVKRMKKERLASNQKNRVDFLQLMMNTQNSKGQESQKALSDLEMAAQAVIFIFGG 306

  Fly   311 FETSGAVLYHMLYSLSEHHEEQEKLRSEILEALASEGQISYDQINNLPYLDQCFNESLRLTTPIG 375
            ::.:...:..::|.|:.|.:.|:||:.||...|.::..::||.:.::.|||...|||||| .||.
Mouse   307 YDATSTSISLIMYELATHPDVQKKLQDEIDRTLPNKAPVTYDALMDMEYLDMVVNESLRL-YPIA 370

  Fly   376 FFM-RICTKPTQINLGDDKTLDLEPGVTVMVPAYQYHHDNDIYPEASEFRPDRF--ENGAASVLT 437
            ..: |:..|..:||     .:.:..|..||:|.|..|.:.:.:||..||.|:||  ||
Mouse   371 IRLERVSKKDVEIN-----GVFIPKGTVVMIPIYPLHRNPEYWPEPQEFCPERFSKEN------- 423

  Fly   438 KRG-----CFLPFGDGPRICLGMRVGQLSVKTAIVHILSNYQVE--QMKKVPL 483
             :|     .::|||:|||.|:|||...:|:|.|::.:|.|:.|:  :..::||
Mouse   424 -KGNIDPYIYMPFGNGPRNCIGMRFALISIKLAVIGVLQNFTVQPCEETQIPL 475

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp309a1	NP_001259943.1	p450	49..481	CDD:299894	117/463 (25%)
Cyp3a25	NP_062766.2	p450	39..493	CDD:278495	123/480 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D264519at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920