Protein Alignment Cyp309a1 and Cyp3a73

DIOPT Version :10

• Sequence 1: NP_608688.3
• Gene: Cyp309a1 / 33438
• FlyBaseID: FBgn0031432
• Length: 506
• Species: Drosophila melanogaster
• Sequence 2: XP_038945885.1
• Gene: Cyp3a73 / 498198
• RGDID: 1595705
• Length: 504
• Species: Rattus norvegicus
• Alignment Length: 506
• Identity: 138/506 - (27%)
• Similarity: 236/506 - (46%)
• Gaps: 71/506 - (14%)

  Fly     7 LCLTIVHVAFAVVYFYLTWYHKYWDKRGVVTAEPLTILGSYPGILINKSRSLILDVQDVYNKYKD 71
            |.|.|:.|.|   |.:.|..|..:.|:|:...:||..||:    ::|..|.|.....:.|.|..
  Rat    13 LLLAIILVLF---YRFGTRTHGIFKKQGIPGPKPLPFLGT----VLNYYRGLWKFDMECYKKCG- 69

  Fly    72 KYRTVGTFITRQPQLLVLDPALAHEILVDK-FSHFRDTITSSFVGHNPDDKYVAGSPFFSAGDKW 135
              :..|.|..:.|...::|..:...:||.: ||.|.:......||      .::.|...:..::|
  Rat    70 --KIWGLFDGQTPVFAIMDTEMIKSVLVKECFSVFTNRRNIGPVG------IMSKSISVAKDEEW 126

  Fly   136 KRLRSENVGGLTPSRLKMAYSIWEQSGRKLVEYIERARREQGDIIETRDLAYRFTANAMADFIWG 200
            ||.|:......|..|||..:.|.|..|..||:|::: :.|:|..:..:::...::.:.:....:.
  Rat   127 KRYRAFLSPTFTSGRLKEMFPIIEHYGDILVKYLKQ-KVEKGKPLAMKEVFGAYSMDVITSTSFE 190

  Fly   201 IDAGSLSGK----VGEIGDFQKTSTDWSAHAFSSMIRFNKTLVAIFVRKLFSMRFFTKATDEFFL 261
            ::..|::..    |.::..||:  .|:....|.|::.| ..|..|:  ::.::..|.|.:..||.
  Rat   191 VNINSINNPKDPFVEKVKKFQR--FDFFDPLFLSVVLF-PFLTPIY--EMLNICLFPKDSVAFFQ 250

  Fly   262 RLTQDAVNLRQGGSGEGRTDYLSHLIQLQQRGNSIHDSVGH-----------ALTVHLDGFETSG 315
            :........|.....:.|.|:|..::...   |:..|.|.|           |:......:||:.
  Rat   251 KFVYRMKQTRLDSKHKHRVDFLQLMMNAH---NNSKDKVSHKALSDIEIVAQAIIFIFASYETTS 312

  Fly   316 AVLYHMLYSLSEHHEEQEKLRSEILEALASEGQISYDQINNLPYLDQCFNESLRLTTPIGFFM-R 379
            :.|..:||||:.|.:.|:||:.||..||.::...:||.:..:.|||...||:.|| .|||:.: |
  Rat   313 STLSFVLYSLATHPDSQKKLQEEIDRALPNKAPPTYDTVMEMEYLDMVLNETPRL-YPIGYRLER 376

  Fly   380 ICTKPTQINLGDDKTLD---LEPGVTVMVPAYQYHHDNDIYPEASEFRPDRF--ENGAASVLTKR 439
            :|.|        |..||   :..|..||:|.|...||...:||..||.|:||  ||        :
  Rat   377 VCKK--------DIKLDGVFIPKGSVVMIPFYTLQHDPQHWPEPEEFLPERFSKEN--------K 425

  Fly   440 G-----CFLPFGDGPRICLGMRVGQLSVKTAIVHILSN--YQVEQMKKVPL 483
            |     .:||||:|||.|:|||...:::|.|:..:|.|  :|:.:..::||
  Rat   426 GSIDPYVYLPFGNGPRNCIGMRFALMNMKLALTKVLQNFSFQLCEETQIPL 476

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp309a1	NP_608688.3	CYP6-like	71..480	CDD:410679	117/437 (27%)
Cyp3a73	XP_038945885.1	CYP3A	67..493	CDD:410743	120/445 (27%)