Protein Alignment Cyp309a1 and LOC4577431

DIOPT Version :10

• Sequence 1: NP_608688.3
• Gene: Cyp309a1 / 33438
• FlyBaseID: FBgn0031432
• Length: 506
• Species: Drosophila melanogaster
• Sequence 2: XP_001237417.1
• Gene: LOC4577431 / 4577431
• VectorBaseID: AGAMI1_011574
• Length: 462
• Species: Anopheles gambiae
• Alignment Length: 529
• Identity: 112/529 - (21%)
• Similarity: 192/529 - (36%)
• Gaps: 128/529 - (24%)

  Fly     6 GLCLTIVHVAFAVVYFYLTWYHKYW-DKRGVVTAEPLTILGSYPGILINKSRSLILDVQDVYNKY 69
            ||||            .|......| |:|...|.....:.|.|..  ..::...|...|.:|.::
Mosquito    21 GLCL------------ILDKRRSLWVDRRFPSTGRTCVLYGDYGA--AGRTEHRIYTTQRLYREF 71

  Fly    70 KDKYRTVG---TFITRQPQLLVLDPALAHEILVDKFSHFRDTITSSFVGHNPDDKYVAGSPFFSA 131
            |.|...:|   .::|  |.::..||.|...:|.::|            |.|.... :|||..|.
Mosquito    72 KSKKWPIGGALMYLT--PCVIPTDPHLIEFLLNEEF------------GKNKKSS-IAGSSIFR- 120

  Fly   132 GDKWKRLRSENVGGLTPSRLKMAYSIWEQSGRKLVEYIERARREQGDIIETRDLAYRFTANAMAD 196
             .:|.....|:...|.        ::..:...|:||.:..:::.    ::.:.:|..:....:|.
Mosquito   121 -KRWSSFEDEHYNSLV--------NVATEESEKVVEMLCTSKQP----VDVKVIAELYAVRMIAR 172

  Fly   197 FIWG-----------IDAGSLSGKVGEIGDFQKTSTDWSAHAFSSMIRFNKTLVAIFVRKLFSMR 250
            .::|           |.....|...|.:.|...|:             |..|.....:|||  :.
Mosquito   173 CVFGKRCTEESHTFPITEKLASQPGGIVWDVFSTA-------------FPSTTFTATLRKL--LD 222

  Fly   251 FFTK---ATDE----FFLRLTQDAVNLRQGGSGEGRTDYLSHLIQLQQRGNSIHDSVG----HAL 304
            .|.|   ..||    |....|.|             .::|.||.:.:||..: ::.:.    .||
Mosquito   223 HFQKHPALLDELVSSFLTERTAD-------------VNFLQHLKRTEQRAKA-NERIAFGDTRAL 273

  Fly   305 TVHLDG---FETSGAVLYHMLYSLSEHHEEQEKLRSEILEALASEGQISYDQINNLPYLDQCFNE 366
            .:.|..   |..||.:: ..|:.:..:.:.|:.|.    |.|......:.|.:.|:      .:|
Mosquito   274 MLELVQNVFFVASGTII-ACLFEMGHNGDIQKGLH----ETLQRSNPFAVDTLENV------ISE 327

  Fly   367 SLRLTTPIGFFMRICTKPTQINLGDDKTLDLEPGVTVMVPAYQYHHDNDIYPEASEFRPDR--FE 429
            :||...|:|....:.....::..|:   |.:.....|:||.|...||.:.||:...|.|.|  |.
Mosquito   328 TLRKYPPVGEISFVTVANNRLPSGE---LVVPKNTRVVVPIYALQHDAEHYPDPERFNPKRSIFS 389

  Fly   430 NGAASVLTKRGCFLPFGDGPRICLGMRVGQLSVKTAIVHILSNYQVEQMKKVP----LGADSGMG 490
            :...|||     :.|.|..| :.:|..:..|.|:.|:.:||....|....:.|    :..:..|.
Mosquito   390 SSEQSVL-----YRPLGVQP-LPIGSSLALLMVRVALSNILGRCTVRLTPESPATLKISPNQAMP 448

  Fly   491 IFLNGDVEL 499
             :..|.|||
Mosquito   449 -YPTGRVEL 456

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp309a1	NP_608688.3	CYP6-like	71..480	CDD:410679	91/438 (21%)
LOC4577431	XP_001237417.1	cytochrome_P450	74..454	CDD:477761	94/458 (21%)