Protein Alignment Cyp309a1 and Tbxas1

DIOPT Version :10

• Sequence 1: NP_608688.3
• Gene: Cyp309a1 / 33438
• FlyBaseID: FBgn0031432
• Length: 506
• Species: Drosophila melanogaster
• Sequence 2: NP_036819.1
• Gene: Tbxas1 / 24886
• RGDID: 3826
• Length: 533
• Species: Rattus norvegicus
• Alignment Length: 557
• Identity: 129/557 - (23%)
• Similarity: 222/557 - (39%)
• Gaps: 107/557 - (19%)

  Fly    10 TIVHVAFAVVYF-YLTWY----HKYWDKRGVVTAEPLTILGSYPGILINKSRSLILDVQDVYNKY 69
            |:|.|..:||.. .|.||    .....|.|:...||...:|           :|:...|..:..:
  Rat    14 TVVTVTLSVVLLALLKWYSTSAFSRLRKLGIRHPEPSPFVG-----------NLMFFRQGFWESH 67

  Fly    70 ---KDKYRTV-GTFITRQPQLLVLDPALAHEILVDKFSHFRDTITSSFVGHNPDDKYVAGSPFFS 130
               :::|..: |.::.|:..:::.||.:..|:||:.||:|.:.:.|..     :.|.:|.|....
  Rat    68 LELRERYGPLCGYYLGRRMYIVISDPDMIKEVLVENFSNFSNRMASGL-----EPKLIADSVLML 127

  Fly   131 AGDKWKRLRSENVGGLTPSRLKMAYSIWEQSGRKLVEYIERARREQGDIIETRDLAYRFTANAMA 195
            ...:|:.:|...:...:|.:|.....:..|:...|:.:::.: ...||..:.:.....||.|.:|
  Rat   128 RDRRWEEVRGALMSAFSPEKLNEMTPLISQACELLLSHLKHS-AASGDAFDIQRCYCCFTTNVVA 191

  Fly   196 DFIWGIDAGSLSGKVGEIGDFQKTSTD-WSAH-----AFSS-------MIRFNKTLVAIFVRKLF 247
            ...:||:..|           |....| :..|     |||:       ::.|...:|.:
  Rat   192 SVAFGIEVNS-----------QDAPEDPFVQHCQRVFAFSTPRPLLALILSFPSIMVPL------ 239

  Fly   248 SMRFF-TKATDE---FFLRLTQDAVNLRQGGSGEGRT-DYLSHLIQLQQRGNS------------ 295
             .|.. .|..||   ||..|.::.:.||...:.|.|. |:|..::..|:..:|
  Rat   240 -ARILPNKNRDELNGFFNTLIRNVIALRDKQTAEERRGDFLQMVLDAQRSMSSVGVEAFDMVTEA 303

  Fly   296 ------------------------IHDSVGHALTVHLDGFETSGAVLYHMLYSLSEHHEEQEKLR 336
                                    :.:..|.|....:.|.|.:...|..:.|.|:.|.|.||:|.
  Rat   304 LSSAECMGDPPQRCHPTSTAKPLTVDEIAGQAFLFLIAGHEITTNTLSFITYLLATHPECQERLL 368

  Fly   337 SEILEALASEGQISYDQI-NNLPYLDQCFNESLRLTTPIGFFMRICTKPTQINLGDDKTLDLEPG 400
            .|:...:.......|..: ..|||||....|:||:..|...|.|...:..:: ||.    .:..|
  Rat   369 KEVDLFMEKHPAPEYCNLQEGLPYLDMVVAETLRMYPPAFRFTREAAQDCEV-LGQ----HIPAG 428

  Fly   401 VTVMVPAYQYHHDNDIYPEASEFRPDRFENGAASVLTKRGCFLPFGDGPRICLGMRVGQLSVKTA 465
            ..:.:.....|||.:.:|....|.|:|| ...|.:..|...:||||.|||.|||:|:|.|.||..
  Rat   429 SVLEIAVGALHHDPEHWPNPETFDPERF-TAEARLQQKPFTYLPFGAGPRSCLGVRLGLLVVKLT 492

  Fly   466 IVHILSNYQVEQM--KKVPLGADSGMGIFLNGDVELK 500
            ::.:|..::.|..  .:|||..:|...:.....|.:|
  Rat   493 LLQVLHKFRFEACPETQVPLQLESKSALCPKNGVYVK 529

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp309a1	NP_608688.3	CYP6-like	71..480	CDD:410679	108/466 (23%)
Tbxas1	NP_036819.1	cytochrome_P450	74..527	CDD:477761	112/482 (23%)