Protein Alignment Cyp309a1 and cyp-13A12

DIOPT Version :10

• Sequence 1: NP_608688.3
• Gene: Cyp309a1 / 33438
• FlyBaseID: FBgn0031432
• Length: 506
• Species: Drosophila melanogaster
• Sequence 2: NP_499705.1
• Gene: cyp-13A12 / 184473
• WormBaseID: WBGene00008810
• Length: 518
• Species: Caenorhabditis elegans
• Alignment Length: 524
• Identity: 129/524 - (24%)
• Similarity: 226/524 - (43%)
• Gaps: 83/524 - (15%)

  Fly     9 LTIVHVAFAVVYFYLTWYHKYWDKRGVVTAEPLTILGSYPGILINKSRSLILDVQDVYNKYKDKY 73
            |.|:.....|:.||| |...||.:||:.......||||...:|.:::.. .|.:::...:|...|
 Worm     6 LAILTSIIGVLSFYL-WTWSYWKRRGIAGPSGYPILGSALEMLSSENPP-YLQLKEWTKQYGKVY 68

  Fly    74 R-TVGTFITRQPQLLVLDPALAHEILVDKFSHFRDTITSSFVGHNPDDKYVAGSPFFSAGDKWKR 137
            . |.|...|    |::.||.|..|:.|.::.:|.....:...|....||.|  :.|.|.|.:|||
 Worm    69 GITEGLSRT----LVISDPDLVQEVFVKQYDNFFGRKLNPIQGDPNKDKRV--NLFSSQGHRWKR 127

  Fly   138 LRSENVGGLTPSRLKMAYSIWEQSGRKLVEYIERARREQGDIIETRDLAYRFTANAMADFIWGID 202
            ||:.:....:.:.|:...:..|:...:|:.:||: ..:.|..|:..|....||.:.:.....|
 Worm   128 LRTISSPTFSNNSLRKLKTTVEECAVELLRHIEQ-HTDGGQPIDLLDFYQEFTLDVIGRIAMG-- 189

  Fly   203 AGSLSGKVGEIGDFQKTSTDWSAHAFSSMIR--FNKTLVAIFV-------------RKLFSMRFF 252
                           :|.:....:.....:|  |.:....:|:             ..:||:...
 Worm   190 ---------------QTDSQMFKNPLLPYVRAVFGEPRKGLFLSGSLAPWIGPILRMVMFSLPNI 239

  Fly   253 TKATDEFFLRLTQDAVNLR--------QGGSGEGR--------TDYLSHLIQLQQ---------- 291
            .|......:|.|.:||..|        :.|...|.        .|..|..::|:.
 Worm   240 VKNPAVHVIRHTSNAVEQRVKLRMADEKAGIDPGEPQDFIDLFLDAKSDDVELENNEDFTKAGVK 304

  Fly   292 --RGNSIHDSVGHALTVHLDGFETSGAVLYHMLYSLSEHHEEQEKLRSEILEALASEGQISYDQI 354
              |..:..:.||......:.||:|:...|.:..:.|:.|.:.|:||:.|| :...::.::::||:
 Worm   305 VTRQLTTEEIVGQCFVFLIAGFDTTALSLSYSSFLLATHPKVQKKLQEEI-DRECADPEVTFDQL 368

  Fly   355 NNLPYLDQCFNESLRLTTPIGFF--MRICTKPTQINLGDDKTLDLEPGVTVMVPAYQYHHDNDIY 417
            :.|.|::....|:||: .|:|..  .|.|.:.|:|.     ..:::.|..::...:..|.|..|:
 Worm   369 SKLKYMECVIKETLRM-YPLGALANSRCCMRATKIG-----NYEIDEGTNILCDTWTLHSDKSIW 427

  Fly   418 PE-ASEFRPDRFENGAASVLTKRGCFLPFGDGPRICLGMRVGQLSVKTAIVHILSNYQVEQMKK- 480
            .| |.||:|:|:|:|......|.| ::|||.|||.|:|||:..:..|..:.|||..|.:|...|
 Worm   428 GEDAEEFKPERWESGDEHFYQKGG-YIPFGLGPRQCIGMRLAYMEEKLLLSHILRKYTLEVCNKT 491

  Fly   481 -VPL 483
             :||
 Worm   492 QIPL 495

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp309a1	NP_608688.3	CYP6-like	71..480	CDD:410679	108/455 (24%)
cyp-13A12	NP_499705.1	CYP3A-like	63..507	CDD:410678	112/465 (24%)