Protein Alignment Cyp309a1 and Cyp3a9

DIOPT Version :10

• Sequence 1: NP_608688.3
• Gene: Cyp309a1 / 33438
• FlyBaseID: FBgn0031432
• Length: 506
• Species: Drosophila melanogaster
• Sequence 2: NP_671739.2
• Gene: Cyp3a9 / 171352
• RGDID: 708392
• Length: 503
• Species: Rattus norvegicus
• Alignment Length: 505
• Identity: 132/505 - (26%)
• Similarity: 225/505 - (44%)
• Gaps: 81/505 - (16%)

  Fly    14 VAFAVVYFYLTWYHKYWDKRGVVTAEPLTILGSYPGILINKSRSLILDVQDVYNKYKDKY----- 73
            ::..::|.|.|..|..:.|.|:...:||..||:            ||..:..:.:: |||
  Rat    17 ISLVLLYLYGTHSHGIFKKLGIPGPKPLPFLGT------------ILAYRKGFWEF-DKYCHKKY 68

  Fly    74 -RTVGTFITRQPQLLVLDPALAHEILVDK-FSHFRDTITSSFVGHNPDDKYVAGSPFFSAGDKWK 136
             :..|.:..|||.|.:.||.:...:||.: :|.|.:......||      .:..:...|..::||
  Rat    69 GKLWGLYDGRQPVLAITDPDIIKTVLVKECYSTFTNRRNFGPVG------ILKKAISISEDEEWK 127

  Fly   137 RLRSENVGGLTPSRLKMAYSIWEQSGRKLVEYIERARREQGDIIETRDLAYRFTANAMADFIWGI 201
            |:|:......|..:||..:.|..|....||..: |...|:|.....:|:...::.:.:....:|:
  Rat   128 RIRALLSPTFTSGKLKEMFPIINQYTDMLVRNM-RQGSEEGKPTSMKDIFGAYSMDVITATSFGV 191

  Fly   202 DAGSLSG-------KVGEIGDFQKTSTDWSAHAFSSMIRFNKTLVAIFVRKLF---SMRFFTKAT 256
            :..||:.       |:.::..|     |.....|.|:..|.      |:..||   ::..|.:..
  Rat   192 NVDSLNNPQDPFVEKIKKLLKF-----DIFDPLFLSVTLFP------FLTPLFEALNVSMFPRDV 245

  Fly   257 DEFFLRLTQDAVNLRQGGSGEGRTDYLSHLIQLQQRGNSIHDS---------VGHALTVHLDGFE 312
            .:||....:.....|.....:.|.|:|..:|..|  .:.:.||         |..::.....|:|
  Rat   246 IDFFKTSVERMKENRMKEKEKQRMDFLQLMINSQ--NSKVKDSHKALSDVEIVAQSVIFIFAGYE 308

  Fly   313 TSGAVLYHMLYSLSEHHEEQEKLRSEILEALASEGQISYDQINNLPYLDQCFNESLRLTTPIGFF 377
            |:.:.|..:||.|:.|.:.|:||:.||..||.::...:||.:..:.|||...||:|||....|..
  Rat   309 TTSSALSFVLYLLAIHPDIQKKLQDEIDAALPNKAHATYDTLLQMEYLDMVVNETLRLYPIAGRL 373

  Fly   378 MRICTKPTQINLGDDKTLDLEPGVTVMVPAYQYHHDNDIYPEASEFRPDRFENGAASVLTKRG-- 440
            .|:|....:||     .:.:..|..||:|.:..|.|...:||..||||:||        :|:.
  Rat   374 ERVCKTDVEIN-----GVFIPKGTVVMIPTFALHKDPHYWPEPEEFRPERF--------SKKNQD 425

  Fly   441 -----CFLPFGDGPRICLGMRVGQLSVKTAIVHILSNYQVEQMK--KVPL 483
                 .:||||:|||.|:|||...:::|.|:|.:|.|:..:..|  ::||
  Rat   426 NINPYMYLPFGNGPRNCIGMRFALMNMKVALVRVLQNFSFQPCKETQIPL 475

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp309a1	NP_608688.3	CYP6-like	71..480	CDD:410679	118/443 (27%)
Cyp3a9	NP_671739.2	CYP3A	67..492	CDD:410743	117/442 (26%)