DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment oaf and OAF

DIOPT Version :9

Sequence 1:	NP_787963.2	Gene:	oaf / 33435	FlyBaseID:	FBgn0011818	Length:	487	Species:	Drosophila melanogaster
Sequence 2:	NP_848602.1	Gene:	OAF / 220323	HGNCID:	28752	Length:	273	Species:	Homo sapiens

Alignment Length:	274	Identity:	106/274 - (38%)
Similarity:	153/274 - (55%)	Gaps:	14/274 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    59 SRAFLWFLLCNLVMNADAFAHSQLLINVQNQGGEVIQESITSNIGEDLITLEFQKTDGTLITQVI 123
            :|..|..||..|.......|.::|.:.|:...|:|.:||:.::...|.|:||.:|.||||::...
Human     9 ARPALLLLLPLLAPLLGTGAPAELRVRVRLPDGQVTEESLQADSDADSISLELRKPDGTLVSFTA 73

  Fly   124 DFRNEVQILKALVLGEEERGQSQYQVMCFATKFNKGDFISSAAMAKLRQKNPHTIRTPEEDKGRE 188
            ||:.:|::.:||:|||.|:||||:|.:||.|:....:.|.|.||||||||||..:|..||.:|.|
Human    74 DFKKDVKVFRALILGELEKGQSQFQALCFVTQLQHNEIIPSEAMAKLRQKNPRAVRQAEEVRGLE 138

  Fly   189 TFTMSSWVQLNRSLPITRHLQGLCAEAMDATYVRDVDLKAWAELPGSSISSLEAATEKFPDTLST 253
            ...|...|..::...::.||..:||||:||.|.|..|::.|.| .|...|..||..:........
Human   139 HLHMDVAVNFSQGALLSPHLHNVCAEAVDAIYTRQEDVRFWLE-QGVDSSVFEALPKASEQAELP 202

  Fly   254 RCNEVSSLWAPCLCNLETCIGWYPCGLKYCKGKGVAGADSSGAQQQAQPTNYRCGIKTCRKCTQF 318
            ||.:|.....||:|.....:.||||.||||..:.             :||.|:|||::|:|...|
Human   203 RCRQVGDHGKPCVCRYGLSLAWYPCMLKYCHSRD-------------RPTPYKCGIRSCQKSYSF 254

  Fly   319 TYYVRQKQQCLWDE 332
            .:||.|:|.|||||
Human   255 DFYVPQRQLCLWDE 268

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
oaf	NP_787963.2	OAF	81..332	CDD:291602	98/250 (39%)
OAF	NP_848602.1	OAF	31..268	CDD:291602	98/250 (39%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165146965
Domainoid	1	1.000	201	1.000	Domainoid score	I3018
eggNOG	1	0.900	-	-		E1_28PQY
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H14334
Inparanoid	1	1.050	203	1.000	Inparanoid score	I3754
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0007195
OrthoInspector	1	1.000	-	-		oto88699
orthoMCL	1	0.900	-	-		OOG6_108566
Panther	1	1.100	-	-	LDO	PTHR13423
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4916
SonicParanoid	1	1.000	-	-		X5307
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	14	13.780