DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Slh and ATSLY1

DIOPT Version :9

Sequence 1:	NP_001137769.2	Gene:	Slh / 33434	FlyBaseID:	FBgn0264978	Length:	639	Species:	Drosophila melanogaster
Sequence 2:	NP_179389.1	Gene:	ATSLY1 / 816310	AraportID:	AT2G17980	Length:	627	Species:	Arabidopsis thaliana

Alignment Length:	645	Identity:	250/645 - (38%)
Similarity:	374/645 - (57%)	Gaps:	33/645 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 LTLRERQINAIKQMLNLNSQ-QPKALAAEPVWKILIYDRVGQDIISPIISIKELRELGVTLHVQL 65
            |.||::|...:.:|||||.. .|...|.|.|:|||||||..|:|:||:..:|:||:.||||...:
plant     3 LNLRQKQTECVIRMLNLNQPLNPSGTANEEVYKILIYDRFCQNILSPLTHVKDLRKHGVTLFFLI 67

  Fly    66 HSDRDSIPDVPAIYFCLPTDENLDRIQQDFSSGLYDVYHLNFLAPITRSKIENLAAAALHAGCVA 130
            ..||..:.||||:||..||:.||.||..|.|..|||.:||||.:.|.|..:|.||:..|.:|.|.
plant    68 DKDRQPVHDVPAVYFVQPTESNLQRIIADASRSLYDTFHLNFSSSIPRKFLEELASGTLKSGSVE 132

  Fly   131 NIHRVYDQYVNFISLEDDFFILKHQQSDQLSYYAINRANTRDEEMEALMDSIVDSLFALFVTLGN 195
            .:.:|:|||:.|::|||:.|.|    :.|.:|..:|..:..::|:..:::.:...||.:.||||.
plant   133 KVSKVHDQYLEFVTLEDNLFSL----AQQSTYVQMNDPSAGEKEINEIIERVASGLFCVLVTLGV 193

  Fly   196 VPIIRCPRNSAAEMVARKLEKKLRENLWDARANLFHMDATQAGGGVFSFQRPVLLLLDRNMDLAT 260
            ||:||||....|||||..|::|||::|. ::.|||    |:.||.:.|||||:|.:.|||.:|:.
plant   194 VPVIRCPSGGPAEMVASLLDQKLRDHLL-SKNNLF----TEGGGFMSSFQRPLLCIFDRNFELSV 253

  Fly   261 PLHHTWSYQALVHDVLDLGLNLVYVEDETASAGARKKPKACDLDRNDRFWMTHKGSPFPTVAEAI 325
            .:.|.:.|:.||||||.|.||.:.|:      |.:..||:.:||.:|.||..:....||.||..|
plant   254 GIQHDFRYRPLVHDVLGLKLNQLKVQ------GEKGPPKSFELDSSDPFWSANSTLEFPDVAVEI 312

  Fly   326 QEELESYRNSEEEIKRLKTSMGIEGESDIAFSLVNDTTARLTNAVNSLPQLMEKKRLIDMHTKIA 390
            :.:|..|:...||:.: ||..|...|.|....:.|..|..|.|.|.|||:|.|:|::||.||.||
plant   313 ETQLNKYKRDVEEVNK-KTGGGSGAEFDGTDLIGNIHTEHLMNTVKSLPELTERKKVIDKHTNIA 376

  Fly   391 TAILNFIKARRLDSFFEIEEKVMSKQTLDRPLLDLLRDGEFGQAEDKLRLYIIYFICAQQLPESE 455
            ||:|..||.|.:|:|.:.|..:|.:..:||..|.....|: |...||||..|:|.|..:.:.:||
plant   377 TALLGQIKERSIDAFTKKESDMMMRGGIDRTELMAALKGK-GTKMDKLRFAIMYLISTETINQSE 440

  Fly   456 QERLKEALQAAGCDLTALAYVQRWKGIMNRSPSISQATQYEGGGTKTVSMFTKLVSQGSSFVMEG 520
            .|.::.||..|..|.:|..||::.|.:   :.|.:..:......:..|....||..|..|.|..|
plant   441 VEAVEAALNEAEADTSAFQYVKKIKSL---NASFAATSANSASRSNIVDWAEKLYGQSISAVTAG 502

  Fly   521 VKNLVVKRHNLPVTKITEQVMECRSNAETDDYLYLDPKLLK----GGEVLPKNRAPFQDAVVFMV 581
            ||||:.....|.||:..|.:.|.:.|.|.|.|.:|||:..|    ||..:   :.||::|:|||:
plant   503 VKNLLSSDQQLAVTRTVEALTEGKPNPEIDSYRFLDPRAPKSSSSGGSHV---KGPFREAIVFMI 564

  Fly   582 GGGNYIEYQNLVDFIKQKQTSNVQRRIIYGASTLTNARQFLKELSALGGE--IQSPTATS 639
            |||||:||.:|.:..:::.|   .:.:||||:.:.|..:.:::|..||.:  :..|.|::
plant   565 GGGNYVEYGSLQELTQRQLT---VKNVIYGATEILNGGELVEQLGLLGKKMGLGGPVAST 621

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Slh	NP_001137769.2	Sec1	1..630	CDD:301618	247/632 (39%)
ATSLY1	NP_179389.1	Sec1	35..598	CDD:395791	231/588 (39%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	394	1.000	Domainoid score	I141
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H5650
Inparanoid	1	1.050	420	1.000	Inparanoid score	I436
OMA	1	1.010	-	-		QHG53926
OrthoDB	1	1.010	-	-		D917326at2759
OrthoFinder	1	1.000	-	-		FOG0004255
OrthoInspector	1	1.000	-	-		oto3893
orthoMCL	1	0.900	-	-		OOG6_101825
Panther	1	1.100	-	-	LDO	PTHR11679
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X3513
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	12	11.980