Protein Alignment Slh and Vps33a

DIOPT Version :9

• Sequence 1: NP_001137769.2
• Gene: Slh / 33434
• FlyBaseID: FBgn0264978
• Length: 639
• Species: Drosophila melanogaster
• Sequence 2: NP_084205.3
• Gene: Vps33a / 77573
• MGIID: 1924823
• Length: 598
• Species: Mus musculus
• Alignment Length: 676
• Identity: 140/676 - (20%)
• Similarity: 241/676 - (35%)
• Gaps: 199/676 - (29%)

  Fly    33 KILIYDRVGQDIISPIISIKELRELGVTLHVQLHSDRDSIPDVPAIYFCL-PTDENLDRIQQDFS 96
            |.:::|.........|.....|:|..|.....|...|....||..|.|.: |..|.:|.|.::..
Mouse    34 KAIVWDEYLTGPFGLIAQYSLLKEHEVEKMFTLKGSRLPAADVKNIIFLVRPRLELMDIIAENVL 98

  Fly    97 S----GLYDVYHLNFL---APITRSKIENLAAAALHAGCVANIHRVYDQY-VNFISLEDDFFILK 153
            |    |....:|:.|:   :.:...::::|....      :.|||  ::| ::.|..:.|...::
Mouse    99 SEDRRGPTRDFHILFVPRRSLLCEQRLKDLGVLG------SFIHR--EEYSLDLIPFDGDLLSME 155

  Fly   154 HQ--------QSDQLSYYAINRANTRDEEMEALMDSIVDSLFALFVTLGNVPII----RCPRNSA 206
            .:        :.||.|.|         ...:.||     :|.||:   |.:|.|    .|.|..|
Mouse   156 SEGAFKECYLEGDQTSLY---------HAAKGLM-----TLQALY---GTIPQIFGKGECARQVA 203

  Fly   207 AEMVARKLEKKLRENLWDARANLFHMDATQAGGGVFSFQRPV---LLLLDRNMDLATPLHHTWSY 268
            ..||..|.|                  .|.:...||    ||   |||||||:||.|||....:|
Mouse   204 NMMVRMKRE------------------FTGSQNSVF----PVFDNLLLLDRNVDLLTPLASQLTY 246

  Fly   269 QALVHDVLDLGLNLVYV---------EDETASAGARKKP---KACDLDRNDRFWMTHKGSPFPTV 321
            :.|:.::  .|:...||         :.:...:|.:..|   |...|:..:..:...:...|..|
Mouse   247 EGLIDEI--YGIQNSYVKLPPEKFAPKKQGGGSGGKDLPTEAKKLQLNSAEELYAEIRDKNFNAV 309

  Fly   322 AEAIQEELESYRNSEEEIKRLKTSMGIEGESDIAFSLVNDTTARLTNAVNSLPQLMEKKRLIDMH 386
            ...:.::.:....:.||....|                  |...:...|:.||.:...:..:..|
Mouse   310 GSVLSKKAKIISAAFEERHNAK------------------TVGEIKQFVSQLPHMQAARGSLANH 356

  Fly   387 TKIATAILNFIKARRLDSFFE---IEEKVMSKQTLDR-------------PLLDLLRDGEFGQAE 435
            |.||..|.:...:   :.||:   :|::.||....|:             ||:.:||
Mouse   357 TSIAELIKDVTTS---EDFFDKLTVEQEFMSGIDTDKVNSYIEDCIAQKHPLIKVLR-------- 410

  Fly   436 DKLRLYIIYFICAQQLPES--EQERL----KEALQAAGCD-------LTALAYVQRWKGIMNRSP 487
                     .:|.|.:..|  :|:.|    :|.||..|.:       |.....::...|..|..|
Mouse   411 ---------LVCLQSVCNSGLKQKVLDYYRREILQTYGYEHILTLNNLEKAGLLKAQTGGRNNYP 466

  Fly   488 SISQATQYEGGGTKTVSMFTKLVSQGS----SFVMEGVKNLVVKRHNL---PVTKITEQVMECRS 545
            :|          .||:.::...|::.:    |:|..|...|.|:...|   |..:..|:|:
Mouse   467 TI----------RKTLRLWMDDVNEQNPTDISYVYSGYAPLSVRLAQLLSRPGWRSIEEVL---- 517

  Fly   546 NAETDDYLYLDPKLLKGGEV---------LPKNRAPFQDAV--VFMVGGGNYIEYQNLVDFIKQK 599
                        ::|.|...         |.|.|.|.::.|  ||.:||..:.|...| .|:.|.
Mouse   518 ------------RILPGPHFEERQPLPTGLQKKRQPGENRVTLVFFLGGVTFAEIAAL-RFLSQL 569

  Fly   600 QTSNVQRRIIYGASTLTNARQFLKEL 625
            :....:  .:...:.|.|...:::.|
Mouse   570 EDGGTE--YVIATTKLMNGNSWIEAL 593

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Slh	NP_001137769.2	Sec1	1..630	CDD:301618	140/676 (21%)
Vps33a	NP_084205.3	Sec1	34..586	CDD:279352	138/667 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910