Protein Alignment Slh and vps45

DIOPT Version :9

• Sequence 1: NP_001137769.2
• Gene: Slh / 33434
• FlyBaseID: FBgn0264978
• Length: 639
• Species: Drosophila melanogaster
• Sequence 2: NP_001243585.1
• Gene: vps45 / 561653
• ZFINID: ZDB-GENE-060503-526
• Length: 568
• Species: Danio rerio
• Alignment Length: 662
• Identity: 154/662 - (23%)
• Similarity: 278/662 - (41%)
• Gaps: 139/662 - (20%)

  Fly    11 AIKQMLNLNSQQPKALAAEPVWKILIYDRVGQDIISPIISIKELRELGVTLHVQLHS-DRDSIPD 74
            |:||.::...:     ::.|..|:|:.|:....|:|.:.:..|:.:..|.|..::.| :||::..
Zfish     6 AVKQYISKMIE-----SSGPGMKVLLMDKETTSIVSVVYTQSEILQKEVYLFERIDSQNRDNMKH 65

  Fly    75 VPAIYFCLPTDENLDRIQQDFSSGLYDVYHLNFLAPITRSKIENLAAAALHAGCVANIHRVYDQY 139
            :.||.|..||.||::.:.|:.....|.||.:.|...|::|:::.||.|. ....||.:...|.
Zfish    66 LKAICFLRPTKENVEHLIQELRRPKYSVYFIYFSNVISKSEVKALAEAD-EQEVVAEVQEFYG-- 127

  Fly   140 VNFISLEDDFFILKHQQSDQLSYYAINRANTRDEEMEALMDSIVDSLFALFVTLGNVPIIRCPRN 204
             :||::....|.|..|        .::|..:.:   .:::..:...|.::.::|...|:||...:
Zfish   128 -DFIAVNPHLFSLNLQ--------GVSRGRSWE---PSVLPRVTQGLTSVLLSLKKCPMIRYQLS 180

  Fly   205 SAAEMVARKLEKKLRENLWDARANLFHMDATQAGGGVFSFQR----PVLLLLDRNMDLATPLHHT 265
            |       .:.|:|.|::.......:.:         |.|::    |:||:|||:.|..|||.:.
Zfish   181 S-------DMSKRLAESVKQIITKEYEL---------FDFRKTEVPPLLLILDRSDDAITPLLNQ 229

  Fly   266 WSYQALVHDVLDLGLNLVYVEDETASAGARKKPKACDLD-RNDRFWMTHKGSPFPTVAEAIQEEL 329
            |:|||:||::|.|..|.:   |.:...|..|..:...|. .||.|:..:....|..:...|:..:
Zfish   230 WTYQAMVHELLGLNNNRI---DLSRVPGISKDLREVVLSAENDEFYANNLYLNFGEIGTNIKNLM 291

  Fly   330 ESYRNSEEEIKRLKTSMGIEGESDI-AFSLVNDTTARLTNAVNSLPQLMEKKRLIDMHTKIATAI 393
            |.::.     |:.|....:|..||: ||             |.:.||..:....:..|..:...:
Zfish   292 EDFQK-----KKPKDQQKLESISDMKAF-------------VENYPQFKKMSGTVSKHVTVVGEL 338

  Fly   394 LNFIKARRLDSFFEIEEKV------MSKQTLDRPLLDLLRDGEFGQAEDKLRLYIIYFICAQQLP 452
            ...:..|:|....|:|:::      .:.|.:.|.||...|..|.    |.:||.::|.:..::..
Zfish   339 SRLVSERQLMEVSEVEQELACQNDHSNAQQMLRRLLQSPRLSEI----DAVRLVMLYALRYEKHS 399

  Fly   453 ESEQERLKEALQAAGCDLTALAYVQRWKGIMNRSPSISQATQYEGG----------GTKTVSMFT 507
            .|....|.|.|..              ||:..|...:..|....||          .|..||: |
Zfish   400 SSILPSLMEELNR--------------KGVSERHRKMVHAVVEYGGKRIRGSDLITPTDAVSI-T 449

  Fly   508 KLVSQGSSFVMEGVKNLVVKRHNLPVTKITEQVMECRSNAETDDYLYLDPKLLKGGEVLPKNRAP 572
            |...:|    ::||:| |..:|...:....:|:::.|  .:...:.||.|..|:...
Zfish   450 KQFFKG----LKGVEN-VYTQHQPLLHDTLDQLIKGR--LKDSQFPYLGPSSLRDRP-------- 499

  Fly   573 FQDAVVFMVGGGNYIEYQNLVDFIKQKQTSNVQR-----RIIYGASTLTNARQFLKEL------- 625
             ||.:||::||..|.|...:.         |:.|     ||:.|.:.:.|.:.||:|:
Zfish   500 -QDIIVFIIGGATYEEALTVY---------NLNRTMPGVRIVLGGTHIHNTKSFLEEVMLSVGSG 554

  Fly   626 ---SALGGEIQS 634
               |.:||...|
Zfish   555 GDRSQIGGRQMS 566

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Slh	NP_001137769.2	Sec1	1..630	CDD:301618	151/656 (23%)
vps45	NP_001243585.1	Sec1	23..539	CDD:279352	142/611 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910