Protein Alignment Slh and stxbp1b

DIOPT Version :9

• Sequence 1: NP_001137769.2
• Gene: Slh / 33434
• FlyBaseID: FBgn0264978
• Length: 639
• Species: Drosophila melanogaster
• Sequence 2: NP_001082845.1
• Gene: stxbp1b / 557717
• ZFINID: ZDB-GENE-060531-166
• Length: 605
• Species: Danio rerio
• Alignment Length: 655
• Identity: 137/655 - (20%)
• Similarity: 264/655 - (40%)
• Gaps: 131/655 - (20%)

  Fly    24 KALAAEPV-------------WKILIYDRVGQDIISPIISIKELRELGVTLHVQLHSDRDSIPDV 75
            ||:..|.:             ||:|:.|::...::|....:.::...|:|:...:...|:.:|.:
Zfish     7 KAIVGEKIMNDVIRKVKKKGEWKVLVVDKLSMRMVSSCCKMTDIMSEGITIVEDITKKREPLPTM 71

  Fly    76 PAIYFCLPTDENLDRIQQDFSSGLYDVY---HLNFLAPITRSKIENLAAAALHAGCVANIHRVYD 137
            .||:...|:||:::.:..||......:|   |:.|...|..| :.||.:.:..:..:..:..:
Zfish    72 EAIFLITPSDESVEGLINDFRDPRNPIYRGAHVFFTDAIPDS-LFNLLSKSRASKSIKTLTEI-- 133

  Fly   138 QYVNFISLEDDFFILKHQQSDQLSYYAINRANTRDEEMEALMDSIVDSLFALFVTLGNVPIIRCP 202
             ::.|:..|...|.:....:.| .:|:..:|:.:::.:|.|.:.|.    .|..||...|.:|..
Zfish   134 -HIAFLPYESQVFSVDKSDAFQ-DFYSPFKADVKNQVLERLAEQIA----TLCATLKEYPAVRYR 192

  Fly   203 ---RNSAAEMVARKLEKKLRENLWDARANLFHMDATQAGGGVFSFQRPVLLLLDRNMDLATPLHH 264
               :::|  ::|:.|:.||         :.:..|....|.|. ...|..||:|||..|..:||.|
Zfish   193 GEYKDNA--VLAQMLQDKL---------DGYKADDPTLGEGP-DKARSQLLILDRGFDPVSPLLH 245

  Fly   265 TWSYQALVHDVLDLGLNLVYVEDETASAGARKKPKACDLDRNDRFWMTHKGSPFPTVAEAIQEEL 329
            ..::||:.:|:|.:. |.||:.:.:.....|.|...  ||.:|..|||.:......|:.|:.:.|
Zfish   246 ELTFQAMAYDLLPIE-NDVYMYETSGMGDTRMKEVL--LDEDDDLWMTLRHKHIAEVSTAVTKSL 307

  Fly   330 ESYRNSEEEIKRLKTSMGIEGESDIAFSLVNDTTARLTNAVNSLPQLMEKKRLIDMHTKIATAIL 394
            :.:..|    |::.|     ||        ..|...|:..:..:||..::......|..:|...:
Zfish   308 KDFSAS----KKMNT-----GE--------KTTMKELSQMLKKMPQYQKELSKYSTHLHLAEDCM 355

  Fly   395 NFIKARRLDSFFEIE-----------EKVMSKQTLDRPLLDLLRDGEFGQAEDKLRLYIIYFICA 448
            ...:. .:|....:|           ||:....   |.::.:|.|... ...||:|:.::|....
Zfish   356 KQYQG-TVDKLCRVEQDLAMGTDAEGEKIKDPM---RAIVPILLDATV-TIMDKIRIILLYIFLK 415

  Fly   449 QQLPESEQERLKEALQAAGCD------LTALAYVQRWKGIMNRSPSIS-QATQYEGGGTKTVSMF 506
            ..:.|   |.|.:.||.|...      ::.:|::    |:    |.|| |||..:|..:......
Zfish   416 NGVSE---ENLCKLLQHAQIPPEDSDIISNMAHM----GV----PIISEQATTRKGKKSDRKERI 469

  Fly   507 TKLVSQGSSFVMEGVKNLVVKRHNLPVTKITEQVME--CRSNAETDDYLYLDPKLLKGGEVLP-- 567
            ::...|.|.:                 |.:.:.:||  .....:...|.|:..:.:.......
Zfish   470 SEQTYQLSRW-----------------TPLVKDIMEDAIEDKLDPKQYPYISTRTVSSKTTTATS 517

  Fly   568 -------KNRAPFQ-----DAVVFMVGGGNYIEYQNLVDFIKQKQTSNVQRRIIYGASTLTNARQ 620
                   ||::|.:     ..:||:|||..|.|.:.:.:.   .|.:.....:|....|:|..:
Zfish   518 ARYGNWHKNKSPGEIRNGPRIIVFIVGGVTYSEMRCVYEV---TQANGKWEALIGSTHTITPVK- 578

  Fly   621 FLKEL 625
            :||.|
Zfish   579 YLKHL 583

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Slh	NP_001137769.2	Sec1	1..630	CDD:301618	137/655 (21%)
stxbp1b	NP_001082845.1	Sec1	29..576	CDD:279352	129/623 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910