Protein Alignment Slh and vps33a

DIOPT Version :9

• Sequence 1: NP_001137769.2
• Gene: Slh / 33434
• FlyBaseID: FBgn0264978
• Length: 639
• Species: Drosophila melanogaster
• Sequence 2: NP_001093443.1
• Gene: vps33a / 448942
• ZFINID: ZDB-GENE-040914-82
• Length: 599
• Species: Danio rerio
• Alignment Length: 698
• Identity: 146/698 - (20%)
• Similarity: 245/698 - (35%)
• Gaps: 198/698 - (28%)

  Fly     4 LRERQINAIKQMLNLNSQQPKALAAEPVWKILIYDRVGQDIISPIISIKELRELGVTLHVQLHSD 68
            |||.....:::.|:..|..          |.:::|.........|.....|:|..|.....|...
Zfish    15 LREAARKDLREFLDKCSGS----------KAIVWDEYLTGPFGLIAQYSLLKEHEVEKMFTLKGG 69

  Fly    69 RDSIPDVPA---IYFCLPTDENLDRIQQDFSSGLYD-----VYHLNFLAPITRSKIENLAAAALH 125
            |  ||....   ::|..|..|.:|.|.::.||  .|     .:|:.|   :.|..:  |....|.
Zfish    70 R--IPSAAVKNIVFFVRPRLELMDIIAENVSS--EDKLQPREFHILF---VPRRSL--LCEQRLK 125

  Fly   126 AGCVANIHRVYDQYV-NFISLEDDFFILKHQQS--------DQLSYYAINRANTRDEEMEALMDS 181
            ...|.|.....|:|: :.|..:.|...::.:.|        ||.|.|         ...:.||
Zfish   126 EKGVLNSFTNIDEYILDLIPYDGDLLSMESESSFRECYLENDQTSLY---------HAAKGLM-- 179

  Fly   182 IVDSLFALFVTLGNVPII----RCPRNSAAEMVARKLEKKLRENLWDARANLFHMDATQAGGGVF 242
               :|.||:   |.:|.|    .|.|:.|..|:..|.|              |....||.
Zfish   180 ---TLQALY---GTIPQIFGKGECARHVANMMLRMKRE--------------FAGSHTQI----- 219

  Fly   243 SFQRPV---LLLLDRNMDLATPLHHTWSYQALVHDVLDLGLNLVYVEDETASAGARK-------- 296
               .||   |||||||:||.|||....:|:.|:.::  .|:...||:........:|
Zfish   220 ---LPVFDTLLLLDRNVDLLTPLATQLTYEGLIDEI--FGITNGYVKLPPEKFAQKKQGEGGKDL 279

  Fly   297 --KPKACDLDRNDRFWMTHKGSPFPTVAEAIQEELESYRNSEEEIKRLKTSMGIEGESDIAFSLV 359
              :||...|:..:..:...:...|..|..|:.::.:....:.||....|
Zfish   280 PTEPKKLQLNSAEELYAEIRDKNFNAVGAALSKKAKIISAAFEERHNAK---------------- 328

  Fly   360 NDTTARLTNAVNSLPQLMEKKRLIDMHTKIATAILNFIKARRLDSFFE---IEEKVMSKQTLDR- 420
              |...:...|:.||.:...:..:..||.||..|.:...:   :.||:   :|::.|:....|:
Zfish   329 --TVGEIKQFVSQLPHMQAARSSLANHTSIAELIKDITTS---EVFFDSLTVEQEFMTGVDTDKV 388

  Fly   421 ------------PLLDLLRDGEFGQAEDKLRLYIIYFICAQQLPESEQERLK-EALQAAGC---- 468
                        ||:.:            |||..:..:|...|.:...:..| |.||..|.
Zfish   389 STYIEDCIAQKDPLIKI------------LRLVCMQSVCNNGLKQKVLDYYKREILQTYGYKHIL 441

  Fly   469 ---DLTALAYVQRWKGIMNRSPSISQATQYEGGGTKTVSMFTKLVSQGS----SFVMEGVKNLVV 526
               :|..:..::....:.|..|:|          .||:.::.:..::.:    |:|..|...|.|
Zfish   442 TLKNLEKVGLLKPQSTMRNNYPTI----------RKTLKLWMEDANEQNPNDISYVYSGYAPLSV 496

  Fly   527 KRHNL---PVTKITEQVMECRSNAETDDYLYLDPKLLKGGEV---------LPKNRAPFQD--AV 577
            :...:   |..:..|:|:                |:|.|...         |.|.|.|.::  .:
Zfish   497 RLTQVLARPGWRSIEEVL----------------KMLPGPHFEERQQVPTGLHKKRQPGENRTTL 545

  Fly   578 VFMVGGGNYIEYQNLVDFIKQKQTSNVQRRIIYGASTLTNARQFLKEL 625
            ||.:||..|.|...| .|:...:.|..:  .|...:.|.|...::|.|
Zfish   546 VFFLGGVTYAEIAAL-RFLSHMEDSGTE--YIIATTKLINGTSWVKSL 590

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Slh	NP_001137769.2	Sec1	1..630	CDD:301618	146/698 (21%)
vps33a	NP_001093443.1	Sec1	34..583	CDD:279352	138/660 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910