Protein Alignment Slh and Rop

DIOPT Version :9

• Sequence 1: NP_001137769.2
• Gene: Slh / 33434
• FlyBaseID: FBgn0264978
• Length: 639
• Species: Drosophila melanogaster
• Sequence 2: NP_001261404.1
• Gene: Rop / 38493
• FlyBaseID: FBgn0004574
• Length: 597
• Species: Drosophila melanogaster
• Alignment Length: 643
• Identity: 135/643 - (20%)
• Similarity: 258/643 - (40%)
• Gaps: 128/643 - (19%)

  Fly    32 WKILIYDRVGQDIISPIISIKELRELGVTLHVQLHSDRDSIPDVPAIYFCLPTDENLDRIQQDFS 96
            |::|:.|::|..::|....:.|:...|:||...::..|:.:|.:.|||...|:||::..:.:||.
  Fly    39 WRVLVVDKLGMRMVSACTKMHEISAEGITLVEDINKKREPLPTMDAIYLITPSDESVRGLIRDFE 103

  Fly    97 S---GLYDVYHLNFLAPITRSKIENLAAAALHAGCVANIHRVYDQYVNFISLEDDFFILKHQQSD 158
            :   .:|...|: |...:...::.|....:..||.:..:..:   .:.|:..|...|.|....:.
  Fly   104 NPARPMYRYAHV-FFTEVCPEELFNDLCKSCAAGKIKTLKEI---NIAFLPYECQVFSLDSPDTF 164

  Fly   159 QLSYYAINRANTRDEEMEALMDSIVDSLFALFVTLGNVPIIR----CPRN-SAAEMVARKLEKKL 218
            | ..|:...|:.|.:.:|.:.:.|.    .|..|||..|.:|    ..|| ..|..|.:||:...
  Fly   165 Q-CLYSPAFASIRSKHIERIAEQIA----TLCATLGEYPNVRYRSDWDRNIDLAASVQQKLDAYK 224

  Fly   219 RENLWDARANLFHMDATQAGGGVFSFQRPVLLLLDRNMDLATPLHHTWSYQALVHDVLDLGLNLV 283
            .:            |||...|.  ...|..||:|||..|..:||.|..:.||:.:|:|.: :|.|
  Fly   225 AD------------DATMGEGP--EKARSQLLILDRGFDCVSPLLHELTLQAMAYDLLPI-VNDV 274

  Fly   284 YVEDETASAGARKKPKACDLDRNDRFWMTHKGSPFPTVAEAIQEELESYRNSEEEIKRLKTSMGI 348
            |    ..:.|..:..|...||.||..|:..:......|:..:.:.|:.:.:|    ||:
  Fly   275 Y----RYTPGPNQPDKEVLLDENDDLWVELRHEHIAVVSTQVTQNLKKFTDS----KRM------ 325

  Fly   349 EGESDIAFSLVNDTTARLTNAVNSLPQLMEKKRLIDMHTKIATAIL----NFIKARRLDSFFEIE 409
             |.:|      ..:...|:..:..:||..::......|..:|...:    |::     |....:|
  Fly   326 -GSAD------KSSMRDLSQMIKKMPQYQKELSKYSTHLHLAEDCMKSYQNYV-----DKLCRVE 378

  Fly   410 -----------EKVMSKQTLDRPLLDLLRDGEFGQAEDKLRLYIIYFICAQ-------------- 449
                       ||:....   |.::.:|.|..... .||:|:..:|.:...
  Fly   379 QDLAMGTDAEGEKIKDHM---RNIVPILLDANVSN-YDKVRIIALYVMIKNGISEENLTKLFTHA 439

  Fly   450 QLPESEQERLKEALQAAGCDLTALAYVQRWKGIMNRSPSISQATQYEGGGTKTVSMFTKLVSQGS 514
            ||...:|:.::. |...|.::.|.:..:::.     .|...:.|:    .|..:|.:|.::..
  Fly   440 QLSPKDQDMVRN-LSCLGINVIADSRKKQYS-----VPRKERTTE----STYQMSRWTPVIKD-- 492

  Fly   515 SFVMEG-VKNLVVKRHNLPVTKITEQVMECRSNAETDDYLYLDPKLLKGGEVLPKNRAPFQDA-- 576
              :||. :::.:..|| .|..:         ..|:..:| :.......|.....|.:|..::.
  Fly   493 --IMEDCIEDKLDLRH-FPFLE---------GRAQNTNY-HAPTSARYGHWHKDKGQAQVKNVPR 544

  Fly   577 -VVFMVGGGNYIEYQNLVDFIKQKQTSNVQR--RIIYGASTLTNARQFLKELSALGGE 631
             :||:|||.:..|.:...      :.:|..|  .::.|:|.:.:...||.:|.:|..|
  Fly   545 LIVFIVGGVSMSEMRCAY------EVTNAVRNWEVLVGSSHILSPEIFLSDLGSLSKE 596

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Slh	NP_001137769.2	Sec1	1..630	CDD:301618	134/640 (21%)
Rop	NP_001261404.1	Sec1	40..583	CDD:395791	129/627 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45464250
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11679
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940