Protein Alignment Slh and scfd1

DIOPT Version :10

• Sequence 1: NP_995614.1
• Gene: Slh / 33434
• FlyBaseID: FBgn0264978
• Length: 639
• Species: Drosophila melanogaster
• Sequence 2: NP_878281.3
• Gene: scfd1 / 317732
• ZFINID: ZDB-GENE-030116-3
• Length: 632
• Species: Danio rerio
• Alignment Length: 638
• Identity: 372/638 - (58%)
• Similarity: 496/638 - (77%)
• Gaps: 22/638 - (3%)

  Fly     3 TLRERQINAIKQMLNLNSQQPKALAAEPVWKILIYDRVGQDIISPIISIKELRELGVTLHVQLHS 67
            ::||:|..|:|:|||.|:...|...||||||:|||||.|||||||::|:||||::|:|||:.|||
Zfish     4 SIREKQTAALKRMLNFNAPPLKNTTAEPVWKVLIYDRFGQDIISPLLSVKELRDMGITLHLLLHS 68

  Fly    68 DRDSIPDVPAIYFCLPTDENLDRIQQDFSSGLYDVYHLNFLAPITRSKIENLAAAALHAGCVANI 132
            |||.|||||||||.:||:||:|||.||..:.||:.|:|||::.|:|||:|::|:|||.|..|..:
Zfish    69 DRDPIPDVPAIYFIMPTEENIDRICQDLRNQLYESYYLNFISAISRSKLEDIASAALAANAVNQV 133

  Fly   133 HRVYDQYVNFISLEDDFFILKHQQSDQLSYYAINRANTRDEEMEALMDSIVDSLFALFVTLGNVP 197
            .:|:|||:|||:||||.|||.:|..:.:||:|||:.:..|.:||.:||:||||||..|||||.||
Zfish   134 TKVFDQYLNFITLEDDMFILCNQNKEHISYHAINKPDIMDTDMEGIMDTIVDSLFCFFVTLGAVP 198

  Fly   198 IIRCPRNSAAEMVARKLEKKLRENLWDARANLFHMDATQAGGGVFSFQRPVLLLLDRNMDLATPL 262
            ||||||.:||||||.||:|||||||.|||.:||..|.  .|.|.||||||:.:|.|||:||||||
Zfish   199 IIRCPRGNAAEMVAVKLDKKLRENLRDARNSLFTGDT--MGTGQFSFQRPLFVLADRNLDLATPL 261

  Fly   263 HHTWSYQALVHDVLDLGLNLVYVED----ETASAGAR---KKPKACDLDRNDRFWMTHKGSPFPT 320
            ||||:||||:|||||..||.|.|::    |.:.||||   |..|:.||...|:||..|||||||.
Zfish   262 HHTWTYQALIHDVLDFHLNRVSVDESHGSEASPAGARPKKKNKKSYDLTAADKFWQKHKGSPFPE 326

  Fly   321 VAEAIQEELESYRNSEEEIKRLKTSMGIEGESDIAFSLVNDTTARLTNAVNSLPQLMEKKRLIDM 385
            ||||:||||::||..|:|:||||:.||:|||.|.|.|:::|.||:||:||:|||:|:|||||||:
Zfish   327 VAEAVQEELDTYRAQEDEVKRLKSIMGLEGEDDGAISMLSDNTAKLTSAVSSLPELLEKKRLIDL 391

  Fly   386 HTKIATAILNFIKARRLDSFFEIEEKVMSKQTLDRPLLDLLRDGEFGQAEDKLRLYIIYFICAQQ 450
            ||.:|||:|:.||:|:||.:||.|||:|||.|||:.|||::.|.:.|.||||:||::||:|.:||
Zfish   392 HTNVATAVLDHIKSRKLDVYFEYEEKLMSKSTLDKSLLDIISDPDAGTAEDKMRLFLIYYITSQQ 456

  Fly   451 LP-ESEQERLKEALQAAGCDLTALAYVQRWKGI--MNRSPSISQATQYEGGGTKTVSMFTKLVSQ 512
            .| |::.|:.|:|:..|||||:.|.|:::||..  |..:|:     .|...|.|.:.:|:::::.
Zfish   457 PPSEADLEQYKKAMVDAGCDLSPLNYIKQWKAFTKMAATPA-----NYGSSGVKPMGLFSRVMNT 516

  Fly   513 GSSFVMEGVKNLVVKRHNLPVTKITEQVMECRSNAETDDYLYLDPKLLKGGE-VLPKNRAPFQDA 576
            ||.||||||||||:|:||||||:|.:.:||.:||.|||||.|.|||:|:|.| .:|:|:.|||:|
Zfish   517 GSQFVMEGVKNLVLKQHNLPVTRILDNLMEMKSNPETDDYRYFDPKMLRGSESSIPRNKNPFQEA 581

  Fly   577 VVFMVGGGNYIEYQNLVDFIKQKQTSNVQRRIIYGASTLTNARQFLKELSALG 629
            :||:||||||||||||||:.|.:|    .:||:||.|.|.||.||:|:||.||
Zfish   582 IVFVVGGGNYIEYQNLVDYTKTRQ----GKRILYGCSELFNAAQFIKQLSQLG 630

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Slh	NP_995614.1	Sec1	33..624	CDD:460020	352/601 (59%)
scfd1	NP_878281.3	None