Protein Alignment Slh and Stxbp1

DIOPT Version :9

• Sequence 1: NP_001137769.2
• Gene: Slh / 33434
• FlyBaseID: FBgn0264978
• Length: 639
• Species: Drosophila melanogaster
• Sequence 2: XP_006234001.1
• Gene: Stxbp1 / 25558
• RGDID: 3785
• Length: 603
• Species: Rattus norvegicus
• Alignment Length: 671
• Identity: 136/671 - (20%)
• Similarity: 271/671 - (40%)
• Gaps: 134/671 - (19%)

  Fly    24 KALAAEPV-------------WKILIYDRVGQDIISPIISIKELRELGVTLHVQLHSDRDSIPDV 75
            ||:..|.:             ||:|:.|::...::|....:.::...|:|:...::..|:.:|.:
  Rat     7 KAVVGEKIMHDVIKKVKKKGEWKVLVVDQLSMRMLSSCCKMTDIMTEGITIVEDINKRREPLPSL 71

  Fly    76 PAIYFCLPTDENLDRIQQDFS---SGLYDVYHLNFLAPITRSKIENLAAAALHAGCVANIHRVYD 137
            .|:|...|:::::..:..||.   :..|...|:.|    |.|..:.|....:.:.....|..:.:
  Rat    72 EAVYLITPSEKSVHSLISDFKDPPTAKYRAAHVFF----TDSCPDALFNELVKSRAAKVIKTLTE 132

  Fly   138 QYVNFISLEDDFFILKHQQSDQLSYYAINRANTRDEEMEALMDSIVDSLFALFVTLGNVPIIRCP 202
            ..:.|:..|...:.|....|.| |:|:.::|..::..:|.|.:.|.    .|..||...|.:|..
  Rat   133 INIAFLPYESQVYSLDSADSFQ-SFYSPHKAQMKNPILERLAEQIA----TLCATLKEYPAVRYR 192

  Fly   203 ---RNSAAEMVARKLEKKLRENLWDARANLFHMDATQAGGGVFSFQRPVLLLLDRNMDLATPLHH 264
               :::|  ::|:.::.||     ||    :..|....|.|. ...|..||:|||..|.::|:.|
  Rat   193 GEYKDNA--LLAQLIQDKL-----DA----YKADDPTMGEGP-DKARSQLLILDRGFDPSSPVLH 245

  Fly   265 TWSYQALVHDVLDLGLNLVYVEDETASAGARKKPKACDLDRNDRFWMTHKGSPFPTVAEAIQEEL 329
            ..::||:.:|:|.:. |.|| :.||:..| ..:.|...||.:|..|:..:......|::.:...|
  Rat   246 ELTFQAMSYDLLPIE-NDVY-KYETSGIG-EARVKEVLLDEDDDLWIALRHKHIAEVSQEVTRSL 307

  Fly   330 ESYRNSEEEIKRLKTSMGIEGESDIAFSLVNDTTAR-LTNAVNSLPQLMEKKRLIDMHTKIATAI 393
            :.:.:|    ||:.|     ||.         ||.| |:..:..:||..::......|..:|...
  Rat   308 KDFSSS----KRMNT-----GEK---------TTMRDLSQMLKKMPQYQKELSKYSTHLHLAEDC 354

  Fly   394 LNFIKARRLDSFFEIE-----------EKVMSKQTLDRPLLDLLRDGEFGQAEDKLRLYIIYFIC 447
            :...:. .:|....:|           ||:....   |.::.:|.|... ...||:|:.::|...
  Rat   355 MKHYQG-TVDKLCRVEQDLAMGTDAEGEKIKDPM---RAIVPILLDANV-STYDKIRIILLYIFL 414

  Fly   448 AQQLPESEQERLKEALQAAGCD---LTALAYVQRWKGIMNRSPSISQATQYEGGGTKTVSMFTKL 509
            ...:.|....:|.:..|....|   :|.:|::    |:    |.::.:|.......:.....::.
  Rat   415 KNGITEENLNKLIQHAQIPPEDSEIITNMAHL----GV----PIVTDSTLRRRSKPERKERISEQ 471

  Fly   510 VSQGSSFVMEGVKNLVVKRHNLPVTKITEQVME--CRSNAETDDYLYLDPKLLKGGEVLP----- 567
            ..|.|.:                 |.|.:.:||  .....:|..|.|:..:.........
  Rat   472 TYQLSRW-----------------TPIIKDIMEDTIEDKLDTKHYPYISTRSSASFSTTAVSARY 519

  Fly   568 ----KNRAPFQ-----DAVVFMVGGGNYIEYQNLVDFIKQKQTSNVQRRIIYGASTLTNARQFL- 622
                ||:||.:     ..::|::||.:..|.:...:..:    :|.:..::.|::.:....:||
  Rat   520 GHWHKNKAPGEYRSGPRLIIFILGGVSLNEMRCAYEVTQ----ANGKWEVLIGSTHILTPTKFLM 580

  Fly   623 -------KELSALGGEIQSPT 636
                   :|.|.:..|.|:||
  Rat   581 DLRHPDFRESSRVSFEDQAPT 601

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Slh	NP_001137769.2	Sec1	1..630	CDD:301618	132/663 (20%)
Stxbp1	XP_006234001.1	Sec1	29..575	CDD:395791	124/621 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910