Protein Alignment Slh and sly1

DIOPT Version :9

• Sequence 1: NP_001137769.2
• Gene: Slh / 33434
• FlyBaseID: FBgn0264978
• Length: 639
• Species: Drosophila melanogaster
• Sequence 2: NP_588374.1
• Gene: sly1 / 2539096
• PomBaseID: SPCC74.01
• Length: 639
• Species: Schizosaccharomyces pombe
• Alignment Length: 656
• Identity: 238/656 - (36%)
• Similarity: 379/656 - (57%)
• Gaps: 58/656 - (8%)

  Fly     3 TLRERQINAIKQMLNLN------SQQPKALAAEPVWKILIYDRVGQDIISPIISIKELRELGVTL 61
            :|||.||.:::::||||      ...|:..:..|:||:||:|:.|.:.||.::.|.:||:.|||:
pombe    11 SLREAQIQSLEKLLNLNQDVNELESSPQHASNFPIWKVLIFDKAGSETISSVLRISDLRKHGVTV 75

  Fly    62 HVQLHSDRDSIPDVPAIYFCLPTDENLDRIQQDFSSGLYDVYHLNFLAPITRSKIENLAAAALHA 126
            |:.:.|.|..|.|||||||..||.||::.|.:|.|.|||:..::.|.:.|:|:.:|..|..|...
pombe    76 HMNITSFRQPIADVPAIYFVQPTQENIELIIEDLSKGLYESAYVCFSSTISRALLEQFAELASKT 140

  Fly   127 GCVANIHRVYDQYVNFISLEDDFFILKHQQSDQLS--YYAINRANTRDEEMEALMDSIVDSLFAL 189
            .....||:|||||:|::.||.|||.|      ||.  ::..:..::.:..:.:.:..||:.||::
pombe   141 NTSHMIHQVYDQYLNYVVLESDFFSL------QLPKIFHTFHNPSSDEALINSRVQDIVNGLFSV 199

  Fly   190 FVTLGNVPIIRCPRNSAAEMVARKLEKKLRENLWDARANLFHMDATQAGGGVFSFQRPVLLLLDR 254
            .||||.:||||||:.|||||||:||.::|:::|         |:...|...|....||:|:||||
pombe   200 IVTLGTIPIIRCPQGSAAEMVAQKLNQRLKDHL---------MNTKDAFVSVNPKPRPILILLDR 255

  Fly   255 NMDLATPLHHTWSYQALVHDVLDLGLNLVYVEDETASAGARKKPKACDLDRNDRFWMTHKGSPFP 319
            .:||...::|:|:||||:||.|::.||.:.|  |:...|...| :..|||.||.||.::...|||
pombe   256 TVDLIPMINHSWTYQALIHDTLNMQLNRITV--ESVDDGKMTK-RFYDLDGNDFFWESNASKPFP 317

  Fly   320 TVAEAIQEELESYRNSEEEIKRLKTSMGIEGESDIAFSLVNDTTARLTNAVNSLPQLMEKKRLID 384
            .|||.|.|||..|:|...||.|   ..|:....::......|:| .|.:||:.||:|..:|:::|
pombe   318 KVAENIDEELTRYKNDASEITR---KSGVSSLEEVNVDAFADST-YLKSAVSLLPELTARKQILD 378

  Fly   385 MHTKIATAILNFIKARRLDSFFEIEEKVMSKQTLDR-PLLDLLRDGEFGQAEDKLRLYIIYFICA 448
            ||..||||:|..|:.|.||.||::|:.:..   |:| .:|..:.:.|.|..|||||.:||:::..
pombe   379 MHMNIATALLKAIQERHLDDFFQLEDNITG---LNRSAILACINNKEQGTPEDKLRFFIIWYLSV 440

  Fly   449 QQLPESEQERLKEALQAAGCDLTALAYVQRWKGIMNRSPSISQATQYEGG-------------GT 500
            ..:|.|:.:..:|||...||.|.||.:|:|.:.|...:...|..|:...|             .|
pombe   441 DSVPASDLQAYEEALVNNGCTLEALNFVKRVREITKMTMLASSTTRPATGQTGDNLFRGFSSLST 505

  Fly   501 KTVSMFTKLVSQGSSFVMEGVKNLVVKRHNLPVTKITEQVMECRS---NAETDDYLYLDPKLLKG 562
            :....|.:....|...::.||:||:..|.:..:|.|.:.:|:..|   :.:|:.||.||||..:.
pombe   506 RFTDRFKEAGIGGLENIISGVRNLIPFRKDGTITSIVQSLMDPGSSPASKQTESYLLLDPKSARA 570

  Fly   563 GEV-----LPKNRAPFQDAVVFMVGGGNYIEYQNLVDFIKQKQTSNVQRRIIYGASTLTNARQFL 622
            ..|     ....|..|.:|:|.::|||||:||.||.|:.:::   |.::|||||::.:.:..:|:
pombe   571 ITVNNDPRAMNKRQTFSEAIVCVLGGGNYLEYGNLADWAREQ---NPKKRIIYGSTDILSPSEFM 632

  Fly   623 KELSAL 628
            :|:::|
pombe   633 EEMASL 638

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Slh	NP_001137769.2	Sec1	1..630	CDD:301618	238/656 (36%)
sly1	NP_588374.1	SEC1	10..639	CDD:227487	238/656 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	372	1.000	Domainoid score	I138
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H5650
Inparanoid	1	1.050	396	1.000	Inparanoid score	I389
OMA	1	1.010	-	-		QHG53926
OrthoFinder	1	1.000	-	-		FOG0004255
OrthoInspector	1	1.000	-	-		oto101643
orthoMCL	1	0.900	-	-		OOG6_101825
Panther	1	1.100	-	-	LDO	PTHR11679
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1350
SonicParanoid	1	1.000	-	-		X3513
TreeFam	0	0.000	Not matched by this tool.
	12	12.000