Protein Alignment Slh and vps-33.2

DIOPT Version :9

• Sequence 1: NP_001137769.2
• Gene: Slh / 33434
• FlyBaseID: FBgn0264978
• Length: 639
• Species: Drosophila melanogaster
• Sequence 2: NP_495342.2
• Gene: vps-33.2 / 174095
• WormBaseID: WBGene00016960
• Length: 617
• Species: Caenorhabditis elegans
• Alignment Length: 712
• Identity: 133/712 - (18%)
• Similarity: 249/712 - (34%)
• Gaps: 183/712 - (25%)

  Fly     6 ERQINAIKQMLNLNSQQP--KALAAEPVWKILIYDRVGQDIISPIISIKELRELGVTLHVQLHSD 68
            |.:|:....:|.:..|:.  ..|...|..|.|..|:.....:..|.:..:::..||..  .:|.|
 Worm     7 ELEIDETLHLLRMVMQREFIHYLETLPGTKELFIDKCLLRPLDMIATSSDMKRHGVKR--IMHFD 69

  Fly    69 RDSIPDV------PAIYFCLPTDEN----LDRIQQDFSSGLYDVYHLNFLAPITRSKIENLAAAA 123
            ....|.|      ..::|..|..||    ::.:::...:....|...|       .::|....|.
 Worm    70 LQKSPQVWNIEIDQRVFFLRPNVENARKIVEYVEESSENRSICVIWCN-------RQLEECDLAF 127

  Fly   124 LHAGCVANIHRVYDQYVNFISLEDDFFILKHQQSDQLSYYAINRANTRDEEMEALMDSIVDSLFA 188
            ..:|.:.:|.:: ...:..:.||.|.|.|:|.:|.|...:::  ||
 Worm   128 ESSGVIGHITQL-SLNMCLLPLESDLFSLQHVESAQPDLFSV--AN------------------- 170

  Fly   189 LFVTLGNV-PIIRCPRNSAAEMVARKLEKKLRENLWDARANLFHMDATQAGGGVFSFQRPV--LL 250
            :||.|.|: .:|.......:|          .:|||:....|...:..:|..     .:|:  |.
 Worm   171 MFVALQNLYGVIPTVYGLGSE----------SKNLWNLVHALCSSNELRARP-----DQPISHLF 220

  Fly   251 LLDRNMDLATPLHHTWSYQALVHD--VLDLGLNLVYVEDETASAGARKKPKACDLDRNDRFWMTH 313
            |.||.:|....|....||:.|:|:  .:|.| .|.:..|      .||:.:...||
 Worm   221 LFDRQLDPVPVLLTGASYEGLLHEFFTIDCG-KLAFPVD------LRKQVQTGPLD--------- 269

  Fly   314 KGSPFPTVAEAIQEELESYRNSEEEIKRLKTSMGIEGESDIAFSLVN-DTTARLT---NAVNSLP 374
                |..:....:|:.|:::.:..:..:|      :...||..|:.| ..||.|.   :...|:.
 Worm   270 ----FDWIEINPEEDKEAHQQNRGDTVKL------DNCEDIFASIRNKHVTAALEFLHSKAKSIQ 324

  Fly   375 QLMEKKRLID------------------------MHTKIATAILNFIKARRLDSFFEIEEK---- 411
            :.:||..:||                        :|......::|.:|.....:.|::|.:
 Worm   325 KSIEKSSMIDDVADYRNFVEKDLRALKKDHKHCELHINACEMMMNKVKMEDYRTMFKLEHEMLLG 389

  Fly   412 -----------------------VMSKQTLDRPLLDLLRDGEFGQ-AEDKLRLYIIYFICAQQLP 452
                                   |:|..:|....||.:.|..:.: .|..|:.|....:.  :|.
 Worm   390 TVTHEEYFDFVFERVPMRSCRDVVLSMMSLASLKLDGVPDDTYNEFVEMYLQKYGYEHMF--ELQ 452

  Fly   453 ESEQERLKEALQAAGCDLTALAYVQRWKGIMNRSPSISQATQYEGGGTKTVSMFTKLVSQGSSFV 517
            .....|:..|.:....|.|.....:.|:.:..:...:.        |.:.:.|..   ....|:|
 Worm   453 NLRNSRVIYARRHIAHDRTISERARTWETLARKFRIVK--------GNEPMDMSN---PSDMSYV 506

  Fly   518 MEGVKNLVVKRHNLPVTKITEQVMECRSN-AETDDYLYLDPKLLKGGEVLPKNRAP----FQDAV 577
            ...       |.:..:.||.|..::...| ||.:..:..|..|::....:..:|.|    .:..:
 Worm   507 FGA-------RISPLLCKIVEDTIDHGWNQAEYERIIGKDKVLVEENTYIAADRRPDNRTRKAIM 564

  Fly   578 VFMVGGGNYIEYQNLVDFIKQKQTSNVQRRIIYGASTLTNARQFLKELSALGGEIQSPTATS 639
            ||:.||..|.|...|.....||..     ||:...:.:...|::|        |:::..|:|
 Worm   565 VFVNGGITYWEVAALRLLAIQKNF-----RILICTTHVIKKREYL--------EVRAKDASS 613

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Slh	NP_001137769.2	Sec1	1..630	CDD:301618	130/701 (19%)
vps-33.2	NP_495342.2	Sec1	36..598	CDD:307231	122/658 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910