Protein Alignment dpp and gdf2

DIOPT Version :9

• Sequence 1: NP_477311.1
• Gene: dpp / 33432
• FlyBaseID: FBgn0000490
• Length: 588
• Species: Drosophila melanogaster
• Sequence 2: NP_001165057.2
• Gene: gdf2 / 563287
• ZFINID: ZDB-GENE-100107-1
• Length: 389
• Species: Danio rerio
• Alignment Length: 450
• Identity: 132/450 - (29%)
• Similarity: 187/450 - (41%)
• Gaps: 122/450 - (27%)

  Fly   170 ESIFVEEPTLVLDREVASINVPANAKAIIAEQGPSTYSKEALIKDKLKPDPSTLVEIEKSLLSLF 234
            :|:|::|..||.|                               |.|....|.|..:::..|...
Zfish    31 DSMFIQEQKLVED-------------------------------DDLNKVESFLGFMKEDFLRKL 64

  Fly   235 NMKRPPKIDRSKIIIPEPMKKLYAEIMGHELDSVNIPKPGLLTKSANTVRSFTHKDSKIDDRFPH 299
            |:...|: :..|:..|:.|.:||..   :..|..:||:       ::.:|||..:|.....|..:
Zfish    65 NLSGVPQ-EHRKVQPPQFMIELYNR---YASDKNSIPR-------SDVIRSFVVQDVIYSIRQGN 118

  Fly   300 HHRFRLHFDVKSIPADEKLKAAELQL---------TRDALSQQVVASRSSANRTRYQVLVYDITR 355
            ..:.||.|:| |||..|::.:.:|:|         ..|.|.       :|.|       |||
Zfish   119 KTQHRLLFNV-SIPNHEEITSVQLRLFTLWHRHKPACDDLF-------TSIN-------VYD--- 165

  Fly   356 VGVRGQREPSYL-LLDTKTVRLNSTDTVSLDVQPAVDRWLASPQRNYGLLVEVRTVRSLKPAPHH 419
              |..::....| |||.:.||.:.....:.||..||..|..|
Zfish   166 --VEYEQNAKILHLLDGRDVRESINTWEAFDVTGAVRIWHES----------------------- 205

  Fly   420 HVRLRRSADEAHERWQH--------------KQPLLFTYTDD-GRHKARSIRDV------SGGEG 463
                ||.|.|.....||              ...::..::|| |..|..|:|.|      ...:.
Zfish   206 ----RRGAGEIQVEVQHSCDSFDISLSLEDNSSAVVIVFSDDLGNRKEESMRKVKEMLVREQQQV 266

  Fly   464 GGKGGRNKRQPRRPTRRKNHDDTCRRHSLYVDFSDVGWDDWIVAPLGYDAYYCHGKCPFPLADHF 528
            |.:...:.|..||  :||..::.|||.||.|:|.|:|||.|||||..||||.|.|.|.|||.|..
Zfish   267 GNQAPVSNRHRRR--KRKAKNNYCRRTSLKVNFKDIGWDKWIVAPPEYDAYECKGVCYFPLTDDV 329

  Fly   529 NSTNHAVVQTLVNNMNPGKVPKACCVPTQLDSVAMLYLNDQSTVVLKNYQEMTVVGCGCR 588
            :.:.|||:|||||..||.|...||||||:||.:|::|.......|...|:||.|..||||
Zfish   330 SPSRHAVIQTLVNLSNPKKANMACCVPTKLDPIAVMYQEKGVITVRHLYEEMKVAKCGCR 389

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dpp	NP_477311.1	TGFb_propeptide	225..444	CDD:279078	52/242 (21%)
		TGFB	487..588	CDD:214556	55/100 (55%)
gdf2	NP_001165057.2	TGFb_propeptide	60..222	CDD:279078	52/219 (24%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	263..284		6/22 (27%)
		TGF_beta	288..388	CDD:278448	54/99 (55%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3900
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810