Protein Alignment dpp and gdf10a

DIOPT Version :9

• Sequence 1: NP_477311.1
• Gene: dpp / 33432
• FlyBaseID: FBgn0000490
• Length: 588
• Species: Drosophila melanogaster
• Sequence 2: XP_691459.3
• Gene: gdf10a / 563003
• ZFINID: ZDB-GENE-090312-17
• Length: 441
• Species: Danio rerio
• Alignment Length: 425
• Identity: 101/425 - (23%)
• Similarity: 178/425 - (41%)
• Gaps: 112/425 - (26%)

  Fly   249 IPEPMKKLYAEIMGHELDSVNIPKPGLLTKSANTVRSFTHKDSKIDDRFPHHHRFRL-------- 305
            :.:.|.|||        :..| .:|..| |..||||||..|...::.|.  .:|..|
Zfish    44 LSQHMYKLY--------EKYN-TEPNRL-KEGNTVRSFKAKPENVEQRV--SYRLNLTSLQGSEV 96

  Fly   306 ------HFDVKSIPAD-----EKLKAAELQLTRDAL--SQQVVASRSSAN--------------- 342
                  ||.....|..     ::.|....::|...|  |.:::....|.|
Zfish    97 ILSSTFHFFFDKRPRQRSWFCKRFKNPSCRITNFPLLPSIRLLFRSPSVNSTTGSLLGNLTVVPH 161

  Fly   343 -----------------RTRYQVLV-----YDITRVGVRGQREPS---YLLLDTKTVRLNSTDTV 382
                             |.|.|:|:     |.......:.|..||   |||:....:.::..::|
Zfish   162 RRGTWQSKDVSVIMKEARDRNQLLITLEFDYGEQYQRYQDQLSPSTLPYLLVYANDLAISEPNSV 226

  Fly   383 SL----------DVQPAVDRWLASPQRNYGLLVEVRTVRSLK-----PAPHHHV-RLRRSADEAH 431
            ::          |.|||     .||..:    .::|..|.|:     |..::.: .:..::.:.|
Zfish   227 AVSLQRYDPFIGDQQPA-----QSPDSS----PDIRVKRELELDFTDPIENNELPEVEYNSFKQH 282

  Fly   432 ERWQHK----QPLLFTYTDDGRHKARSIRDVSGGEGGGKGGRNKRQPRRPTRRKNHDD--TCRRH 490
            :.|:..    :|..|.     :.:.|..::.:.|.|..:..|...:..:..||:...:  :|.|.
Zfish   283 DMWESAYYPLKPKPFK-----KERRRKGQEHTDGFGKSQVLRFDEKTMKKARRRQWKEPRSCSRR 342

  Fly   491 SLYVDFSDVGWDDWIVAPLGYDAYYCHGKCPFPLADHFNSTNHAVVQTLVNNMN--PGKVPKACC 553
            .|.|||:|:||::||::|..:||:||.|.|.||:......:|||.:|::|..:.  || :|:.||
Zfish   343 YLKVDFADIGWNEWILSPKSFDAFYCAGTCEFPIPKVVRPSNHATIQSIVKAVGIIPG-IPEPCC 406

  Fly   554 VPTQLDSVAMLYLNDQSTVVLKNYQEMTVVGCGCR 588
            ||.::..:::|::::...:|||.|..|:|..|.||
Zfish   407 VPEKMKPLSVLFVDESKNIVLKIYPNMSVETCACR 441

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dpp	NP_477311.1	TGFb_propeptide	225..444	CDD:279078	53/275 (19%)
		TGFB	487..588	CDD:214556	40/102 (39%)
gdf10a	XP_691459.3	TGF_beta	337..440	CDD:278448	40/103 (39%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3900
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.810