Protein Alignment dpp and bmp2

DIOPT Version :9

• Sequence 1: NP_477311.1
• Gene: dpp / 33432
• FlyBaseID: FBgn0000490
• Length: 588
• Species: Drosophila melanogaster
• Sequence 2: NP_001015963.1
• Gene: bmp2 / 548717
• XenbaseID: XB-GENE-481829
• Length: 398
• Species: Xenopus tropicalis
• Alignment Length: 403
• Identity: 167/403 - (41%)
• Similarity: 232/403 - (57%)
• Gaps: 39/403 - (9%)

  Fly   197 IIAEQGPSTYSKEALIKDKLKPDPSTLVEIEKSLLSLFNMKRPPKIDRSKIIIPEPMKKLYAEIM 261
            :|.|:|...|::..  :...:...|.|.:.|..||::|.:||.|...:: |:||..|..||....
 Frog    24 LIPEEGKRKYTESG--RSSPQHSQSVLNQFELRLLNMFGLKRRPTPGKN-IVIPPYMLDLYHLHS 85

  Fly   262 GH-ELDSVNIPKPGLLTKS---ANTVRSFTHKDSKIDDRFPHHHR---FRLHFDVKSIPADEKLK 319
            |. ..|..:.|....:.::   |||||||.|::|.  :..|....   .|..|::.|:|.:|.:.
 Frog    86 GQLAADQDSSPMDYQIERAASRANTVRSFHHEESM--EEIPESGEKTIQRFFFNLSSVPNEELVT 148

  Fly   320 AAELQLTRDALSQQVVASRSSANRTRYQVLVYDITRVGVRGQREPSYLLLDTKTVRLNSTDTVSL 384
            :|||::.|:.:.:......|..:|    :.:|||.:......|.|...||||:.:..|.:...|.
 Frog   149 SAELRIFREGVQEPFEGDSSKLHR----INIYDIVKPAAAASRGPVVRLLDTRLIHHNESKWESF 209

  Fly   385 DVQPAVDRWLASPQRNYGLLVEVRTVRSLKPAPHHHVRLRRSADEAHERWQHKQPLLFTYTDDGR 449
            ||.||:.||:|..|.|:|.:|||..:.:.|..|..|||:.||.....:.|...:|||.|::.||:
 Frog   210 DVTPAITRWIAHKQPNHGFVVEVTHLDNDKNVPKKHVRISRSLVPDKDSWPRIRPLLVTFSHDGK 274

  Fly   450 ----HKARSIRDVSGGEGGGKGGRNKRQPRRPTRRKNHDDTCRRHSLYVDFSDVGWDDWIVAPLG 510
                ||                 |.|||.|. .:||....:||||.||||||||||:||||||.|
 Frog   275 GHALHK-----------------REKRQARH-KQRKRLKSSCRRHPLYVDFSDVGWNDWIVAPPG 321

  Fly   511 YDAYYCHGKCPFPLADHFNSTNHAVVQTLVNNMNPGKVPKACCVPTQLDSVAMLYLNDQSTVVLK 575
            |.|:||||:||||||||.||||||:|||||||:|| .:||||||||:|.:::||||::...||||
 Frog   322 YHAFYCHGECPFPLADHLNSTNHAIVQTLVNNVNP-NIPKACCVPTELSAISMLYLDENEKVVLK 385

  Fly   576 NYQEMTVVGCGCR 588
            |||:|.|.|||||
 Frog   386 NYQDMVVEGCGCR 398

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dpp	NP_477311.1	TGFb_propeptide	225..444	CDD:279078	72/225 (32%)
		TGFB	487..588	CDD:214556	75/100 (75%)
bmp2	NP_001015963.1	TGFb_propeptide	34..269	CDD:366248	74/243 (30%)
		TGF_beta_BMP2_like	298..398	CDD:381638	75/100 (75%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	179	1.000	Domainoid score	I3476
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H926
Inparanoid	1	1.050	290	1.000	Inparanoid score	I2745
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002405
OrthoInspector	1	1.000	-	-		otm47971
Panther	1	1.100	-	-	LDO	PTHR11848
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3241
SonicParanoid	1	1.000	-	-		X157
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	9	9.090