Protein Alignment dpp and Gdf3

DIOPT Version :9

• Sequence 1: NP_477311.1
• Gene: dpp / 33432
• FlyBaseID: FBgn0000490
• Length: 588
• Species: Drosophila melanogaster
• Sequence 2: NP_001103141.1
• Gene: Gdf3 / 500311
• RGDID: 1564178
• Length: 366
• Species: Rattus norvegicus
• Alignment Length: 368
• Identity: 95/368 - (25%)
• Similarity: 164/368 - (44%)
• Gaps: 44/368 - (11%)

  Fly   231 LSLFNMKRPPKIDRSKIIIPEPMKKLY-----AEIMGHELDSVNIPKPGLLTKSANTVRSFTHKD 290
            |....:|:.|...|.: .:|..::|:.     |...|...|...:.:.|:   ..|.:|....:.
  Rat    31 LQFLGLKKAPSPHRFQ-PVPRILRKIIRARETAAASGASQDLCYVKELGV---RGNLLRLLPDQG 91

  Fly   291 SKIDDRFPHHH----RFRLHFDVKSIPADEKLKAAELQLTRDALSQQVVASRSSANRTRYQVLVY 351
            ..::.:.|...    :..|.|::.::....||..|:|.|.....|...:       :....|.|.
  Rat    92 FFLNTQKPSQDGSCLQKVLSFNLSAVKEKGKLTMAQLILHLGPRSYHYL-------QLELVVAVS 149

  Fly   352 DITRVGVRGQREPSY-LLLDTKTVRLNSTDTVSLDVQPAVDRWLASPQRNYGLLVEVRTVRSLKP 415
            .:...||.|:..|.. .||..|:| |....::..::|..|..|.....:|..|.:|:.....
  Rat   150 VVQDRGVWGRSHPKLGRLLVQKSV-LGPQGSLQFNLQGVVKDWNRHQLKNLDLYLEILVKED--- 210

  Fly   416 APHHHVRLRRSADEAHERWQHK-QPLLFTYTDDGRHKARSIRDVSGGEGGGKGGRNKRQPRRPTR 479
               .:.|:....|....:..|. ...|...|.:.:|...|.|              |::...|..
  Rat   211 ---RYSRVNAQLDNPCNQLMHSLHASLLVVTLNLKHCHPSSR--------------KKRAAIPIP 258

  Fly   480 RKNHDDTCRRHSLYVDFSDVGWDDWIVAPLGYDAYYCHGKCPFPLADHFNSTNHAVVQTLVNNMN 544
            :....:.|.||.|:|:|.|:||..|::||.|:.|.||||.|||.:..:.||:|:|.:|.|::..:
  Rat   259 KGLCRNLCHRHQLFVNFQDLGWHKWVIAPKGFMANYCHGDCPFTMTTYLNSSNYAFMQALMHMAD 323

  Fly   545 PGKVPKACCVPTQLDSVAMLYLNDQSTVVLKNYQEMTVVGCGC 587
            | :||||.|:||:|..::|||.:::..|:|::|::|.|..|||
  Rat   324 P-RVPKAVCIPTKLSPISMLYQDNEKNVILRHYEDMVVDECGC 365

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dpp	NP_477311.1	TGFb_propeptide	225..444	CDD:279078	42/223 (19%)
		TGFB	487..588	CDD:214556	47/101 (47%)
Gdf3	NP_001103141.1	TGFB	266..366	CDD:214556	47/101 (47%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3900
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	4	3.770