Protein Alignment dpp and Lefty1

DIOPT Version :9

• Sequence 1: NP_477311.1
• Gene: dpp / 33432
• FlyBaseID: FBgn0000490
• Length: 588
• Species: Drosophila melanogaster
• Sequence 2: NP_001102550.1
• Gene: Lefty1 / 498299
• RGDID: 1561867
• Length: 368
• Species: Rattus norvegicus
• Alignment Length: 393
• Identity: 86/393 - (21%)
• Similarity: 146/393 - (37%)
• Gaps: 101/393 - (25%)

  Fly   229 SLLSLFNMKRPPKIDRSKI---IIPEPMKKLYAEIMGHELDSVNIPKPGLLTKSANTVRSFTHKD 290
            |||....:.|||.:|::.:   :||..::..|..::.|..|            |.:..:.|:...
  Rat    30 SLLQQLRLDRPPVLDKADVEGMVIPSHVRAQYVALLQHSHD------------SRSRGKRFSQNF 82

  Fly   291 SKIDDRF------PHHHRFRLHFDVKSIPADEKLKAAELQL-----TRDALSQQVVASRSSANRT 344
            .::..||      .|...|.:.   :.:|.:.:|..|.|:|     .|.||.:|   .|.|.:..
  Rat    83 REVAGRFLVSETSSHLLVFGME---QRLPPNSELVQAVLRLFQEPVPRTALRRQ---KRLSPHSA 141

  Fly   345 RYQVLVYDITRVGVRGQREPSYLLLDTKTVRLNSTDTVSLDVQPAVDRWLASPQRNYGLLVEVRT 409
            |.:|.: :..|....|....:  |:|::.|.::.:.....||..||:.|....:....||::|..
  Rat   142 RARVTI-EWLRFREDGSNRTA--LIDSRLVSIHESGWKVFDVTEAVNFWQQLSRPRQPLLLQVSV 203

  Fly   410 VRS-LKPAP-HHHVRLRRSADEAHERWQHKQPLLFTYTDDGRHKARSIRDVSGGEGGGKGGRNKR 472
            .|. |.|.. ..|..:|.:|....:.....:|.|..:|.|       ::|.        |.:...
  Rat   204 QREHLGPGTWSAHKLVRFAAQGTPDGKGLGEPQLELHTLD-------LKDY--------GAQGNC 253

  Fly   473 QPRRPTRRKNHDDTCRRHSLYVDFSDVGW-DDWIVAPLGYDAYYCHGKC-----------PFPLA 525
            .|..|.   .....|.|..:|:|...:.| ::||:.|.|:..|.|.|.|           ||
  Rat   254 DPETPV---TEGTRCCRQEMYLDLQGMKWAENWILEPPGFLTYECVGSCLQPPESLTIRWPF--- 312

  Fly   526 DHFNSTNHAVVQTLVNNMNPGKVPKACCVPTQLDSVAML--YLNDQST----VVLKNYQEMTVVG 584
                             :.|.:     ||.:::.|:.::  ...|..|    |.|.|   |.|..
  Rat   313 -----------------LGPRQ-----CVASEMTSLPLIVSIKEDGRTRPQVVSLPN---MRVQR 352

  Fly   585 CGC 587
            |.|
  Rat   353 CSC 355

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dpp	NP_477311.1	TGFb_propeptide	225..444	CDD:279078	52/230 (23%)
		TGFB	487..588	CDD:214556	28/119 (24%)
Lefty1	NP_001102550.1	TGFb_propeptide	29..211	CDD:413528	46/201 (23%)
		TGF_beta_LEFTY1_2	264..355	CDD:381636	27/118 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3900
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810