Protein Alignment dpp and amh

DIOPT Version :9

• Sequence 1: NP_477311.1
• Gene: dpp / 33432
• FlyBaseID: FBgn0000490
• Length: 588
• Species: Drosophila melanogaster
• Sequence 2: NP_001007780.1
• Gene: amh / 493624
• ZFINID: ZDB-GENE-050706-192
• Length: 549
• Species: Danio rerio
• Alignment Length: 616
• Identity: 136/616 - (22%)
• Similarity: 215/616 - (34%)
• Gaps: 197/616 - (31%)

  Fly    72 NPFSEPASFSDSDK--------SHRSKTNKKPSKSDANRQFNEVHKPRTDQLE------------ 116
            ||...|.|..:.|:        .||.:...:.:..|.  .||:..|...:.|.
Zfish    32 NPKVNPLSELNGDQLEVRDLACVHRQQPTDQHATEDT--PFNKEQKTLNEFLSALKSAGELGKMD 94

  Fly   117 -----NSKNKSKQLVNKPNHNKMAVKEQRSHHKKSHHHRSHQPKQASASTESHQSSSIESIFVEE 176
                 :|:.:|.|:    :|...:|.:::|..|..|           |:.:...:.:.|.|.:
Zfish    95 FLGTCSSETQSSQV----SHLVQSVLQKQSGLKGVH-----------ATEDIWDADNEEGITL-- 142

  Fly   177 PTLVLDREVASINVPANAKAIIAEQGPST----YSKEALIKDKLK---------PDPSTLVEIEK 228
             ||...:.    ::||         ||::    :|...:..|.|:         |:..|:...|.
Zfish   143 -TLTFPKH----SLPA---------GPASVMLLFSVNPVKGDSLRVQFNSQSIHPNTQTVCISES 193

  Fly   229 SLLSL---------FNMKRPPKIDRSKIIIPEPMKKLYAEIMGHELDSVNIPKPGLLTKSANTVR 284
            :...:         .::|....::.|   :.:..:||...    ||:.|.:.|   :..|:.|::
Zfish   194 TRFLIVTGGWSHGHIHLKLKTMVETS---MDDNRRKLSVS----ELNEVLMRK---VDGSSTTIK 248

  Fly   285 SFTHKDSKIDDRFPHHHRFRLHFDVKSIPADEKLKA------AELQ-LTRDALSQQVVASRSSAN 342
            ......|.:|:  ||..|.|       ||.||:|.:      .||| ..||.|.|    |:|:.
Zfish   249 PVLLFLSDLDE--PHLKRHR-------IPQDERLPSRTYLFLCELQKFLRDILPQ----SKSTT- 299

  Fly   343 RTRYQVLVYDITRVGVRGQREPSYLLLDT----KTVRLNSTDTVSL------DVQPAVDRWLASP 397
                             .|.:||.:.|||    ..:||..:.|.||      ...|.|   ...|
Zfish   300 -----------------PQDDPSAVSLDTLHSLPPLRLGVSSTESLLSGLVNSSTPTV---FVFP 344

  Fly   398 QRNYGLLVEVRTVRSLKPAPHHHVRLRRSADEAH-------------ERWQHKQPLLFTYTDDGR 449
            ||..||  :...|.....:|...| ||...|||.             :|.| |...|...:.||.
Zfish   345 QRQQGL--QTHRVEVTLDSPLLSV-LRMRLDEAMAQVKQQEAGRKMIDRLQ-KLTELSALSPDGE 405

  Fly   450 --------HKARSIRDV----------SGGEGGGKGGRNKRQPRRPTRRKNHDDTCRRHSLYVDF 496
                    ||....|.|          |..|    ..|.:|..|......:..:.|...||.|..
Zfish   406 DSEAATKDHKEAQYRSVLLLKALQMVLSNWE----SERAQRAARADEDGPSASNQCHLQSLSVSL 466

  Fly   497 SDVGWDDWIVAPLGYDAYYCHGKCPFPLADHFNSTNHAVVQTLVNNMNPGKVP---KACCVPTQL 558
            .     .:.:.|...:...|.|.|.|||.   |:.||||   |:|:......|   ..||||.:.
Zfish   467 R-----KFFLEPSRANINNCEGTCGFPLN---NANNHAV---LLNSHIQSGQPVNRSLCCVPVEY 520

  Fly   559 DSVAMLYLNDQSTVVLKNYQ-EMTVVGCGCR 588
            |.:.::.|..::|.:  :|: .:....|.||
Zfish   521 DDLCVIELESETTNI--SYKTNVVATKCECR 549

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dpp	NP_477311.1	TGFb_propeptide	225..444	CDD:279078	61/257 (24%)
		TGFB	487..588	CDD:214556	28/104 (27%)
amh	NP_001007780.1	AMH_N	74..439	CDD:282552	93/447 (21%)
		TGF_beta	455..548	CDD:278448	28/105 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3900
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900