Protein Alignment dpp and nodal3.1

DIOPT Version :9

• Sequence 1: NP_477311.1
• Gene: dpp / 33432
• FlyBaseID: FBgn0000490
• Length: 588
• Species: Drosophila melanogaster
• Sequence 2: NP_988864.1
• Gene: nodal3.1 / 394458
• XenbaseID: XB-GENE-5964399
• Length: 401
• Species: Xenopus tropicalis
• Alignment Length: 442
• Identity: 101/442 - (22%)
• Similarity: 172/442 - (38%)
• Gaps: 130/442 - (29%)

  Fly   229 SLLSLF--------NMKRPPKIDRSKII----------------------IPEPMKKLYAEIMG- 262
            :.||||        .|..||.:...|.|                      .|..|.:||..|:.
 Frog     2 AFLSLFLCLVFSSPLMAMPPALQGRKAISPASILKGPSTDNGARDFHGRKFPHFMMQLYQNIISR 66

  Fly   263 HELDSVNIPKPGLLTKSANTVRSFTHKDSKIDDRFPHHHRFRLHFDVKSIPADEKLKAAELQL-- 325
            .:.|..|:..|.|  :.::||:||..|......     :.:.|.||:.||..:.:||.|||::
 Frog    67 RDKDLSNLEHPTL--QESDTVQSFIAKSYTTVG-----NHWTLFFDMSSISTNNELKLAELRICL 124

  Fly   326 ---------------TRDALSQQVVASRSS--ANRTRYQVLVYDITRVGVRGQREPSYLLLDTKT 373
                           |:|...:..:.|..:  ::.......|:::|.|      ..:||:...:.
 Frog   125 PSFGKSHSVTVEIYHTKDTKEKLFMGSFKTKISSALDADCKVFNLTMV------LHNYLIRGKRL 183

  Fly   374 VRLNSTDTVSLDVQPAVDRWLASPQRNYGLLVE----------VRTVRSLKPAPHHHVRLRRSAD 428
            ::               |.::.:.    |||:.          ...|.:||...||   :...|.
 Frog   184 IK---------------DEYIQAK----GLLLRDLEKSAAEKGAENVDTLKQDKHH---VSDFAA 226

  Fly   429 E-------AHERWQHKQ----------PLLFTYTDDGRHKARSIRDVSGGEGGGKGGRNKRQPRR 476
            |       |.||.|.|.          ||.:...|:. :|....|.:.         |||::..|
 Frog   227 ERIILVVFAKERSQAKPDPPSLGKQLFPLKYGMADNA-NKVNGFRRLR---------RNKKEKTR 281

  Fly   477 -------PTRRKNHDDTCRRHSLYVDFSDVGWDDWIVAPLGYDAYYCHGKCPFPLADHFNSTNHA 534
                   |...:.....||:..::|||..:||..|||.|..|:||.|...|..||.:..::||::
 Frog   282 MDVGTTPPKPVEEIKPKCRKVDMFVDFQKIGWGSWIVYPKAYNAYRCESACAVPLNETDDATNYS 346

  Fly   535 VVQTLVNNMNPGKVPKACCVPTQLDSVAMLYLNDQSTVVLKNYQEMTVVGCG 586
            .:::|:...:..:.....|||.::.|::|||..::. .:|::::||.|..||
 Frog   347 YIKSLLPLSDTERRECPSCVPVKMRSMSMLYYENEE-FILRHHEEMIVEECG 397

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dpp	NP_477311.1	TGFb_propeptide	225..444	CDD:279078	59/291 (20%)
		TGFB	487..588	CDD:214556	34/100 (34%)
nodal3.1	NP_988864.1	TGFb_propeptide	53..>139	CDD:279078	24/92 (26%)
		TGFB	299..397	CDD:214556	32/98 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910