Protein Alignment dpp and INHBB

DIOPT Version :9

• Sequence 1: NP_477311.1
• Gene: dpp / 33432
• FlyBaseID: FBgn0000490
• Length: 588
• Species: Drosophila melanogaster
• Sequence 2: NP_002184.2
• Gene: INHBB / 3625
• HGNCID: 6067
• Length: 407
• Species: Homo sapiens
• Alignment Length: 382
• Identity: 96/382 - (25%)
• Similarity: 157/382 - (41%)
• Gaps: 59/382 - (15%)

  Fly   219 DPSTLVEIEKSLLSLFNMKRPPKIDRS--KIIIPEPMKKLYAEIMGHELDSVNIP------KPGL 275
            |...|..:::.:||...|:..|.|..:  |..:...::||:|..: .|...|.||      .||.
Human    71 DGDFLEAVKRHILSRLQMRGRPNITHAVPKAAMVTALRKLHAGKV-REDGRVEIPHLDGHASPGA 134

  Fly   276 -LTKSANTVRSFTHKDSKIDDRFPHHHRFRLHFDVKSIPADEKLKAAELQLTRDALSQQVVASRS 339
             ..:..:.:.||...|.....      |.||:|.: |...::.|...:..|.........|..:.
Human   135 DGQERVSEIISFAETDGLASS------RVRLYFFI-SNEGNQNLFVVQASLWLYLKLLPYVLEKG 192

  Fly   340 SANRTRYQVLVYDITRVGVRGQREPSYLLLDTKTVRLNSTDTVSLDVQPAVDRWLASPQRNYGLL 404
            |..:.|.:|...:      :|..:...::  .|.|.|..:...:..:..|:.......:|...|.
Human   193 SRRKVRVKVYFQE------QGHGDRWNMV--EKRVDLKRSGWHTFPLTEAIQALFERGERRLNLD 249

  Fly   405 VEVRTVRSLKPAPHHHVRLRRSADEAHERWQHKQPLLFTYTDDGRHKARSIRDVSGGEGGGKGGR 469
            |:..:.:.|...|    ......:|:|..:...|..|    .|.||:.|.    .|.|..|:
Human   250 VQCDSCQELAVVP----VFVDPGEESHRPFVVVQARL----GDSRHRIRK----RGLECDGR--- 299

  Fly   470 NKRQPRRPTRRKNHDDTCRRHSLYVDFSDVGWDDWIVAPLGYDAYYCHGKCPFPLA---DHFNST 531
                          .:.|.|...::||..:||:|||:||.||...||.|.||..||   ...:|.
Human   300 --------------TNLCCRQQFFIDFRLIGWNDWIIAPTGYYGNYCEGSCPAYLAGVPGSASSF 350

  Fly   532 NHAVV-QTLVNNMNPGKVPKACCVPTQLDSVAMLYLNDQSTVVLKNYQEMTVVGCGC 587
            :.||| |..:..:|||.| .:||:||:|.:::|||.:|:..:|.::...|.|..|||
Human   351 HTAVVNQYRMRGLNPGTV-NSCCIPTKLSTMSMLYFDDEYNIVKRDVPNMIVEECGC 406

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dpp	NP_477311.1	TGFb_propeptide	225..444	CDD:279078	43/227 (19%)
		TGFB	487..588	CDD:214556	44/105 (42%)
INHBB	NP_002184.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	26..62
		TGFb_propeptide	57..278	CDD:279078	43/226 (19%)
		TGFB	303..406	CDD:214556	42/103 (41%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3900
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810