Protein Alignment dpp and Lefty2

DIOPT Version :9

• Sequence 1: NP_477311.1
• Gene: dpp / 33432
• FlyBaseID: FBgn0000490
• Length: 588
• Species: Drosophila melanogaster
• Sequence 2: NP_796073.1
• Gene: Lefty2 / 320202
• MGIID: 2443573
• Length: 368
• Species: Mus musculus
• Alignment Length: 402
• Identity: 79/402 - (19%)
• Similarity: 143/402 - (35%)
• Gaps: 111/402 - (27%)

  Fly   225 EIEKSLLSLFNMKRPPKIDRS---KIIIPEPMKKLYAEIMGHELDSVNIPKPGLLTKSANTVRSF 286
            ::..|||....:.:.|.:|.:   ::.||..::..|..::                       ..
Mouse    26 QVLSSLLQQLQLSQAPTLDSADVEEMAIPTHVRSQYVALL-----------------------QG 67

  Fly   287 THKDSKIDDRFPHHHR-------------FRLHFDVKS-IPADEKLKAAELQLTRDALSQQVVA- 336
            :|.|.....||..:.|             ..|.|.::. :|.:.:|..|.|:|.::.:.:..:.
Mouse    68 SHADRSRGKRFSQNFREVAGRFLMSETSTHLLVFGMEQRLPPNSELVQAVLRLFQEPVPRTALRR 132

  Fly   337 -SRSSANRTRYQVLVYDITRVGVRGQREPSYLLLDTKTVRLNSTDTVSLDVQPAVDRWLASPQRN 400
             .|.|.:..|.:|.: :..||...|....:  |:|::.|.::.:...:.||..||:.|....:..
Mouse   133 FERLSPHSARARVTI-EWLRVREDGSNRTA--LIDSRLVSIHESGWKAFDVTEAVNFWQQLSRPR 194

  Fly   401 YGLLVEVRTVRS-LKPAP-HHHVRLRRSADEAHERWQHKQPLLFTYTDDGRHKARSIRDVSGGEG 463
            ..||::|...|. |.|.. ..|..:|.:|....:.....:|.|..:|.|       ::|.
Mouse   195 QPLLLQVSVQREHLGPGTWSAHKLVRFAAQGTPDGKGQGEPQLELHTLD-------LKDY----- 247

  Fly   464 GGKGGRNKRQPRRPTRRKNHDDTCRRHSLYVDFSDVGW-DDWIVAPLGYDAYYCHGKC------- 520
               |.:....|..|.   .....|.|..:|:|...:.| ::||:.|.|:..|.|.|.|
Mouse   248 ---GAQGNCDPEVPV---TEGTRCCRQEMYLDLQGMKWAENWILEPPGFLTYECVGSCLQLPESL 306

  Fly   521 ----PFPLADHFNSTNHAVVQTLVNNMNPGKVPKACCVPTQLDSVAMLYLNDQ------STVVLK 575
                ||                    :.|.:     ||.:::.|:.|:....:      ..|.|.
Mouse   307 TIGWPF--------------------LGPRQ-----CVASEMTSLPMIVSVKEGGRTRPQVVSLP 346

  Fly   576 NYQEMTVVGCGC 587
            |   |.|..|.|
Mouse   347 N---MRVQTCSC 355

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dpp	NP_477311.1	TGFb_propeptide	225..444	CDD:279078	46/239 (19%)
		TGFB	487..588	CDD:214556	27/119 (23%)
Lefty2	NP_796073.1	TGFb_propeptide	<106..211	CDD:279078	25/107 (23%)
		TGF_beta	263..355	CDD:278448	26/119 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3900
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810