Protein Alignment dpp and bmp2b

DIOPT Version :9

• Sequence 1: NP_477311.1
• Gene: dpp / 33432
• FlyBaseID: FBgn0000490
• Length: 588
• Species: Drosophila melanogaster
• Sequence 2: NP_571435.1
• Gene: bmp2b / 30632
• ZFINID: ZDB-GENE-980526-474
• Length: 411
• Species: Danio rerio
• Alignment Length: 403
• Identity: 165/403 - (40%)
• Similarity: 225/403 - (55%)
• Gaps: 65/403 - (16%)

  Fly   217 KPDPSTLVEIEKSLLSLFNMKRPPKIDRSKIIIPEPMKKLYAEIMGHELDSVNIPKP-------- 273
            :.|.:.|.|.|..||::|.:||.|...:| .::|:.|..||  .|..|.|..||.:|
Zfish    43 RTDTNFLNEFELRLLNMFGLKRKPTPSKS-AVVPQYMLDLY--YMHSENDDPNIRRPRSTMGKHV 104

  Fly   274 GLLTKSANTVRSFTHKDS---------KIDDRFPHHHRFRLHFDVKSIPADEKLKAAELQLTRDA 329
            ......|||:|||.|:::         |...:|        .|::.|||.:|.:.||||::.||
Zfish   105 ERAASRANTIRSFHHEEAFEALSSLKGKTTQQF--------FFNLTSIPGEELISAAELRIFRD- 160

  Fly   330 LSQQVVASRSSANRTRYQVLVYDITRVGVRGQREPSYLLLDTKTVRLNSTDTVSLDVQPAVDRWL 394
               ||:...|::.  .:::.:|::.|..:...:||...||||:.|:.:.|...|.||..||.||.
Zfish   161 ---QVLGDASTSG--FHRINIYEVFRPALAPSKEPLTRLLDTRLVQDSHTRWESFDVGSAVARWA 220

  Fly   395 ASPQRNYGLLVEVRTVRSLKPAP-----------HHHVRLRRSADEAHERWQHKQPLLFTYTDDG 448
            ...|.|:||||||     |.|..           ..|||:.||.....:.|...:|||.||:.||
Zfish   221 RESQHNHGLLVEV-----LHPKESEVSEEAESNRRKHVRVSRSLHADEDSWAQARPLLVTYSHDG 280

  Fly   449 RHKARSIRDVSGGEGGGKGGRNKRQPRR--PTRRKNHD-DTCRRHSLYVDFSDVGWDDWIVAPLG 510
            :           |.......|.|||.||  ..|||:|. ..||||:||||||||||::|||||.|
Zfish   281 Q-----------GTAVLHSNREKRQARRGQKPRRKHHQRSNCRRHALYVDFSDVGWNEWIVAPPG 334

  Fly   511 YDAYYCHGKCPFPLADHFNSTNHAVVQTLVNNMNPGKVPKACCVPTQLDSVAMLYLNDQSTVVLK 575
            |.|:||||:|||||.||.||||||:||||||::| ..:|||||:||:|..:::|||::...|:||
Zfish   335 YHAFYCHGECPFPLPDHLNSTNHAIVQTLVNSVN-SNIPKACCIPTELSPISLLYLDEYEKVILK 398

  Fly   576 NYQEMTVVGCGCR 588
            |||:|.|.|||||
Zfish   399 NYQDMVVEGCGCR 411

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dpp	NP_477311.1	TGFb_propeptide	225..444	CDD:279078	78/246 (32%)
		TGFB	487..588	CDD:214556	68/100 (68%)
bmp2b	NP_571435.1	TGFb_propeptide	49..276	CDD:366248	79/248 (32%)
		TGF_beta_BMP2_like	311..411	CDD:381638	68/100 (68%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	177	1.000	Domainoid score	I3545
eggNOG	1	0.900	-	-		E1_KOG3900
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H926
Inparanoid	1	1.050	273	1.000	Inparanoid score	I2952
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002405
OrthoInspector	1	1.000	-	-		otm24629
orthoMCL	1	0.900	-	-		OOG6_105711
Panther	1	1.100	-	-	LDO	PTHR11848
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3241
SonicParanoid	1	1.000	-	-		X157
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	11	10.890