Protein Alignment dpp and bmp2a

DIOPT Version :10

• Sequence 1: NP_477311.1
• Gene: dpp / 33432
• FlyBaseID: FBgn0000490
• Length: 588
• Species: Drosophila melanogaster
• Sequence 2: NP_571434.1
• Gene: bmp2a / 30631
• ZFINID: ZDB-GENE-980526-388
• Length: 386
• Species: Danio rerio
• Alignment Length: 413
• Identity: 159/413 - (38%)
• Similarity: 228/413 - (55%)
• Gaps: 61/413 - (14%)

  Fly   192 ANAKAIIAEQGPSTYSKEALIKDKLKPDPSTLVEIEKSLLSLFNMKRPPKIDRSKIIIPEPMKKL 256
            |.:..::.:.|.|:.|            |..|...|..|||:|.::..|....| .::|:.|..|
Zfish    19 AGSSGLVPQVGRSSLS------------PDVLHAFELRLLSMFGLQHRPTPSTS-AVVPQYMLDL 70

  Fly   257 YAEIMGHELDSVNIPKP-GLLTKS-------ANTVRSFTHKDSKIDDRFPHHHRF--RLHFDVKS 311
            |:   .|.:::..:.:| ..|.|.       |||:||| |.|...:|......|.  |..|::.|
Zfish    71 YS---AHSVNAEQVSRPRAHLGKGSERSASRANTIRSF-HHDESTEDPSSSSVRTTQRFLFNLTS 131

  Fly   312 IPADEKLKAAELQLTRDALSQQVVASRSSANRTRYQVLVYDITRVGVRGQREPSYLLLDTKTVRL 376
            ||.:|.:.:|::::.|    :|:|:|.::|:...:::.|::|.|.. ...:||...||||:.|:.
Zfish   132 IPDEELVTSADVRVFR----EQIVSSLNNASAGFHRINVHEIIRPS-GSLQEPITRLLDTRLVQH 191

  Fly   377 NSTDTVSLDVQPAVDRWLASPQRNYGLLVEVRTVRSLKPAPH------HHVRLRRSADEAHERWQ 435
            :.:...|.||.|||.:|......|:|:|||:         .|      .|||:.||.....:.|.
Zfish   192 SLSKWESFDVTPAVLKWTTDGHPNHGILVEI---------SHPDQDSRKHVRVSRSLHNNEDTWS 247

  Fly   436 HKQPLLFTYTDDGRHKARSIRDVSGGEGGGKGGRNKRQPRRPTRRKNHDDTCRRHSLYVDFSDVG 500
            ..:|||.||:.||:             |.....|.|||.|...:||.|...||||||||||||||
Zfish   248 QMRPLLVTYSHDGK-------------GNVLHSREKRQARNNKQRKKHKANCRRHSLYVDFSDVG 299

  Fly   501 WDDWIVAPLGYDAYYCHGKCPFPLADHFNSTNHAVVQTLVNNMNPGKVPKACCVPTQLDSVAMLY 565
            |:||||||.||.|:||.|:||||||||.|||.:|:||||||::| ..:|:||||||.|..|::||
Zfish   300 WNDWIVAPPGYHAFYCQGECPFPLADHLNSTTNAMVQTLVNSVN-SNIPRACCVPTDLSPVSLLY 363

  Fly   566 LNDQSTVVLKNYQEMTVVGCGCR 588
            |::...|:|||||:|.|.|||||
Zfish   364 LDEYERVILKNYQDMVVEGCGCR 386

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dpp	NP_477311.1	TGFb_propeptide	225..444	CDD:480997	69/234 (29%)
		TGF_beta_DPP	480..588	CDD:381662	72/107 (67%)
bmp2a	NP_571434.1	TGFb_propeptide	40..256	CDD:459906	69/234 (29%)
		TGF_beta_BMP2_like	286..386	CDD:381638	69/100 (69%)