Protein Alignment dpp and bmp4

DIOPT Version :9

• Sequence 1: NP_477311.1
• Gene: dpp / 33432
• FlyBaseID: FBgn0000490
• Length: 588
• Species: Drosophila melanogaster
• Sequence 2: NP_571417.1
• Gene: bmp4 / 30612
• ZFINID: ZDB-GENE-980528-2059
• Length: 400
• Species: Danio rerio
• Alignment Length: 408
• Identity: 165/408 - (40%)
• Similarity: 233/408 - (57%)
• Gaps: 47/408 - (11%)

  Fly   202 GPSTYSKEALIKDKLKPDPST---------LVEIEKSLLSLFNMKRPPKIDRSKIIIPEPMKKLY 257
            |.|:|:  :||.::.|...|.         |.:.|.:||.:|.::|.|:...| .::|:.:..||
Zfish    19 GESSYA--SLIPEEGKKKASALHLAQSHELLRDFEATLLHMFGLQRRPRPSHS-AVVPQYLLDLY 80

  Fly   258 AEIMGHELDS-----VNIPKPGLLTKSANTVRSFTHKD--SKIDDRFPHHHRFRLHFDVKSIPAD 315
             .:...||:.     |:...|...|..|||||.|.|::  .::..........|..|::.|||.|
Zfish    81 -RLQSGELEEAGAQHVSFDYPERSTSRANTVRGFHHEEHLEELQSDGSQETPLRFVFNLSSIPED 144

  Fly   316 EKLKAAELQLTRDALSQQVVASRSSANRT----RYQVLVYDITRVGVRGQREPSYLLLDTKTVRL 376
            |.:..|||::.|    ||:..:.|..::|    .:::.:|::.:....||....  ||||:.||.
Zfish   145 ELISTAELRVYR----QQIDDAFSDPDQTGDHGLHRINIYEVLKAPREGQLITQ--LLDTRLVRH 203

  Fly   377 NSTDTVSLDVQPAVDRWLASPQRNYGLLVEVRTVRSLKPAPHHHVRLRRSADE-AHERWQHKQPL 440
            |::...|.||.|||.||....:.|:||.|||..::........|||:.||... ..|.|...:||
Zfish   204 NTSKWESFDVSPAVLRWTQEKRSNHGLAVEVVQMKRNPVQKGRHVRVSRSVHPLPDEEWDQLRPL 268

  Fly   441 LFTYTDDGRHKARSIRDVSGGEGGGKGGRNKRQPRRPTRRKNHDDTCRRHSLYVDFSDVGWDDWI 505
            |.|:..||:....:             .|.||.|::..|::|.:  ||||:||||||||||:|||
Zfish   269 LVTFGHDGKSHPLT-------------RRAKRSPKQRGRKRNRN--CRRHALYVDFSDVGWNDWI 318

  Fly   506 VAPLGYDAYYCHGKCPFPLADHFNSTNHAVVQTLVNNMNPGKVPKACCVPTQLDSVAMLYLNDQS 570
            |||.||.||||||:||||||||.||||||:||||||::|. .:||||||||:|.:::||||::..
Zfish   319 VAPPGYQAYYCHGECPFPLADHLNSTNHAIVQTLVNSVNT-NIPKACCVPTELSAISMLYLDETD 382

  Fly   571 TVVLKNYQEMTVVGCGCR 588
            .|||||||||.|.|||||
Zfish   383 RVVLKNYQEMVVEGCGCR 400

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dpp	NP_477311.1	TGFb_propeptide	225..444	CDD:279078	71/230 (31%)
		TGFB	487..588	CDD:214556	75/100 (75%)
bmp4	NP_571417.1	TGFb_propeptide	35..272	CDD:279078	73/244 (30%)
		TGFB	300..400	CDD:214556	75/100 (75%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	177	1.000	Domainoid score	I3545
eggNOG	1	0.900	-	-		E1_KOG3900
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	273	1.000	Inparanoid score	I2952
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002405
OrthoInspector	1	1.000	-	-		otm24629
orthoMCL	1	0.900	-	-		OOG6_105711
Panther	1	1.100	-	-	O	PTHR11848
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3241
SonicParanoid	1	1.000	-	-		X157
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	10	9.890