Protein Alignment dpp and lft2

DIOPT Version :9

• Sequence 1: NP_477311.1
• Gene: dpp / 33432
• FlyBaseID: FBgn0000490
• Length: 588
• Species: Drosophila melanogaster
• Sequence 2: NP_571036.1
• Gene: lft2 / 30146
• ZFINID: ZDB-GENE-990630-11
• Length: 362
• Species: Danio rerio
• Alignment Length: 390
• Identity: 90/390 - (23%)
• Similarity: 155/390 - (39%)
• Gaps: 86/390 - (22%)

  Fly   225 EIEKSLLSLFNMKRPPKI---DRSKIIIPEPMKKLYAEI--MGHELDSVNIPKPGLLTKSANTVR 284
            :|:::||....:..||:|   |...:::|..:|..|..:  :.|:....::|      ..|..:|
Zfish    24 DIKQALLQKLGLTEPPRIQKRDLENLVVPAHIKSKYLSMLKLHHQRRRRSLP------SLAGILR 82

  Fly   285 SFTHKDSKI--DDRFPHHHRFRLHFDVKS-IPADEKLKAAELQLTRDALSQQVVASRSSANRTRY 346
            .. |.::.|  :.::....|.||.||::: :..:.::..|||:     |.|....|.|...|..:
Zfish    83 GI-HGNADITGEIKYSDTTRQRLVFDMEARLQENTEVTMAELK-----LFQTAAQSPSKPERRHH 141

  Fly   347 QVLVYDITRVGV-------RGQREPSYLLLDTKTVRLNSTDTVSLDVQPAVDRWLASPQRNYGLL 404
            :.:.:  .||.:       .|....|  |||::.|.::.:...|.||..|:..|..| |:...|.
Zfish   142 RPINH--ARVSIYWVEVLENGSNRTS--LLDSRLVPIHESGWRSFDVTQAIHYWSKS-QKKAPLH 201

  Fly   405 VEVRTVRSLKP---APHHHVRLRRSADEAHERWQHKQ---PLLFTYTDDGRHKARSIRDVSGGEG 463
            :||.| ...:|   |.....|:|.:..:..|....|.   |.|..||.|        .|..|.:|
Zfish   202 LEVWT-EGERPGSYAAEMAKRVRFATQDPKENTLEKDMGAPELVLYTLD--------LDEYGSQG 257

  Fly   464 GGKGGRNKRQPRRPTRRKNHDDTCRRHSLYVDFSDVGWDD-WIVAPLGYDAYYCHGKCPFPLADH 527
            ......|..:             |.|...:::|.::.|.. ||:.|.||.|:.|.|.|..|....
Zfish   258 NCNSSPNSSK-------------CCREEHFINFRELTWTQYWIIEPAGYQAFRCAGGCKQPKRGF 309

  Fly   528 FNSTNHAVVQTLVNNMNPGKVPKACCVPTQLDS--VAMLYL---NDQSTVVLKNYQEMTVVGCGC 587
            :                 |...:.|.|   ::|  :.|:||   .|.:.:.:..:..|.|..|||
Zfish   310 Y-----------------GYGQRTCAV---MESAPLPMMYLVKKGDYTEIEVAEFPNMIVEKCGC 354

  Fly   588  587
            Zfish   355  354

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dpp	NP_477311.1	TGFb_propeptide	225..444	CDD:279078	56/239 (23%)
		TGFB	487..588	CDD:214556	27/107 (25%)
lft2	NP_571036.1	TGFb_propeptide	15..204	CDD:366248	45/196 (23%)
		TGF_beta_LEFTY1_2	267..354	CDD:381636	25/119 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3900
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810