DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment dpp and inhbaa

DIOPT Version :9

Sequence 1:	NP_477311.1	Gene:	dpp / 33432	FlyBaseID:	FBgn0000490	Length:	588	Species:	Drosophila melanogaster
Sequence 2:	NP_001349183.1	Gene:	inhbaa / 30072	ZFINID:	ZDB-GENE-000210-21	Length:	395	Species:	Danio rerio

Alignment Length:	148	Identity:	51/148 - (34%)
Similarity:	72/148 - (48%)	Gaps:	29/148 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   467 GGRNKRQPRRP---------------TRRKNHDD------TCRRHSLYVDFSDVGWDDWIVAPLG 510
            ||..:.|..||               .|||...:      .|.:...||:|.|:||:|||:||.|
Zfish   249 GGSEREQSHRPFLMAVVRQMDELSLRRRRKRGLECDGKARVCCKRQFYVNFKDIGWNDWIIAPSG 313

  Fly   511 YDAYYCHGKCPFPLAD------HFNSTNHAVVQTLVNNMNPGKVPKACCVPTQLDSVAMLYLNDQ 569
            |.|.||.|.|...:|.      .|:||  .:....:...:|....|:|||||:|.:::|||.|::
Zfish   314 YHANYCEGDCASNVASITGNSLSFHST--VISHYRIRGYSPFTNIKSCCVPTRLRAMSMLYYNEE 376

  Fly   570 STVVLKNYQEMTVVGCGC 587
            ..:|.|:.|.|.|..|||
Zfish   377 QKIVKKDIQNMIVEECGC 394

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpp	NP_477311.1	TGFb_propeptide	225..444	CDD:279078
dpp	NP_477311.1	TGFB	487..588	CDD:214556	43/107 (40%)
inhbaa	NP_001349183.1	TGFb_propeptide	67..263	CDD:307025	5/13 (38%)
inhbaa	NP_001349183.1	TGF_beta	290..394	CDD:306518	41/105 (39%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3900
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.810