Protein Alignment dpp and Gdf15

DIOPT Version :9

• Sequence 1: NP_477311.1
• Gene: dpp / 33432
• FlyBaseID: FBgn0000490
• Length: 588
• Species: Drosophila melanogaster
• Sequence 2: NP_062089.1
• Gene: Gdf15 / 29455
• RGDID: 2674
• Length: 303
• Species: Rattus norvegicus
• Alignment Length: 308
• Identity: 78/308 - (25%)
• Similarity: 126/308 - (40%)
• Gaps: 69/308 - (22%)

  Fly   308 DVKSIPADEKLKAAELQLTRDALSQQVVASRSSANRTRYQVLVYDITRVGVRGQREPSYLLLDTK 372
            |..::| :::...:|.||..|.|            |.|:|.|   ::|:.....||.|
  Rat    36 DALALP-EQRRSLSESQLNPDEL------------RGRFQDL---LSRLHANQSREDS------- 77

  Fly   373 TVRLNSTDTVSLDVQPAVDRWLASPQRNYG----LLVEVRTVRSLKPAPHHHVRLRRS---ADEA 430
                ||..|    ..|||.  :.||:...|    ||:.|......:..|..: |:.|:   ...:
  Rat    78 ----NSEPT----PDPAVR--ILSPEVRLGSHGRLLLRVNRASLTQGLPEAY-RVHRALLLLTPS 131

  Fly   431 HERWQHKQPLLFTYTDDGRHKARSIR-------DV----SGG--------EGGGKGGRNKRQPRR 476
            ...|...:||....:..|.| ||::|       |:    |||        ...|:|.|:.....|
  Rat   132 SRPWDITRPLQRAISLQGPH-ARALRLRLAPPPDLAVLPSGGARLELHLRSAAGRGRRSAHLHPR 195

  Fly   477 PTRRKNHDDTCRRHSLYVDFSDVGWDDWIVAPLGYDAYYCHGKCPFPLADH-FNSTN-HAVVQTL 539
            .:........|...::.....|:||.||:::|.......|.|:||     | :.|.| ||:::..
  Rat   196 DSCPLGPGRCCHLETVQATLEDLGWSDWVLSPRQLQLSMCVGECP-----HLYRSANTHALIKAR 255

  Fly   540 VNNMNPGKVPKACCVPTQLDSVAMLYLNDQSTVVLKNYQEMTVVGCGC 587
            ::.:.|.:||..||||:....|.:::..| |.|.|:.|.::...||.|
  Rat   256 LHGLQPDRVPAPCCVPSSYTPVVLMHRTD-SGVSLQTYDDLVAQGCHC 302

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dpp	NP_477311.1	TGFb_propeptide	225..444	CDD:279078	33/142 (23%)
		TGFB	487..588	CDD:214556	32/103 (31%)
Gdf15	NP_062089.1	TGF_beta	204..302	CDD:278448	31/103 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3900
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810