Protein Alignment dpp and Nodal

DIOPT Version :9

• Sequence 1: NP_477311.1
• Gene: dpp / 33432
• FlyBaseID: FBgn0000490
• Length: 588
• Species: Drosophila melanogaster
• Sequence 2: NP_001099864.1
• Gene: Nodal / 294503
• RGDID: 1305994
• Length: 354
• Species: Rattus norvegicus
• Alignment Length: 377
• Identity: 92/377 - (24%)
• Similarity: 156/377 - (41%)
• Gaps: 101/377 - (26%)

  Fly   250 PEP---MKKLYAEIMGHELDSVNIPKPGLLTKSANTVRSFTHKDSKIDDRFPHHHRFRLHFDVKS 311
            |.|   |..||.:           |.|     .|:.:||...:|..:..:     .:...||...
  Rat    39 PSPLAYMLSLYRD-----------PLP-----RADIIRSLQAQDVDVTGQ-----NWTFTFDFSF 82

  Fly   312 IPADEKLKAAELQLTRDALSQQVVASRSSANRTRYQVLVYDITRVGVRGQREPSYLLLDTKTVRL 376
            :..:|.|..|||:|       |:::...|..:....:.::...:..  .:::|:..|......|:
  Rat    83 LSQEEDLVWAELRL-------QLLSPMDSPTKGPLTIDIFHQAKPD--PEQDPADCLERVWMERI 138

  Fly   377 NST--------DTVSLDVQPAVDRWLASPQRNYGLLVEVRTVRSLKPAPHHHVRLRRSADEAHER 433
            ..|        |:..|:|...:.:||..|             |:|:         ::.:.:|.:.
  Rat   139 TVTPSQVTFASDSTVLEVTKPLSKWLKDP-------------RALE---------KQVSSQAGKC 181

  Fly   434 W--QHKQP-------LLFTYTDDGRHKARSIRDVSGG-------------------EGGGKGGRN 470
            |  .|.||       :|..|:    ::.:..|.:.|.                   |..| .||.
  Rat   182 WHQSHTQPVPVTSTSVLMLYS----NRPQEQRQLGGATLLWEAESSWRAQEGQLSVERSG-WGRR 241

  Fly   471 KRQPRRPTRRKNHDDTCRRHSLYVDFSDVGWDDWIVAPLGYDAYYCHGKCPFPLADHFNSTNHAV 535
            :|:...|.|    ...|||....|||:.:||..||:.|..|:||.|.|:||.|:.:.|:.||||.
  Rat   242 QRRHHLPDR----SQLCRRVKFQVDFNLIGWGSWIIYPKQYNAYRCEGECPNPVGEEFHPTNHAY 302

  Fly   536 VQTLVNNMNPGKVPKACCVPTQLDSVAMLYLNDQSTVVLKNYQEMTVVGCGC 587
            :|:|:....|.:||..||.|.:...::|||: |...|:|:::::|.|..|||
  Rat   303 IQSLLKRYQPHRVPSTCCAPVKTKPLSMLYV-DNGRVLLEHHKDMIVEECGC 353

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dpp	NP_477311.1	TGFb_propeptide	225..444	CDD:279078	39/213 (18%)
		TGFB	487..588	CDD:214556	43/101 (43%)
Nodal	NP_001099864.1	TGFb_propeptide	33..169	CDD:279078	31/172 (18%)
		TGFB	254..353	CDD:214556	41/99 (41%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3900
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810