Protein Alignment dpp and Inhba

DIOPT Version :9

• Sequence 1: NP_477311.1
• Gene: dpp / 33432
• FlyBaseID: FBgn0000490
• Length: 588
• Species: Drosophila melanogaster
• Sequence 2: NP_058824.1
• Gene: Inhba / 29200
• RGDID: 62074
• Length: 424
• Species: Rattus norvegicus
• Alignment Length: 476
• Identity: 107/476 - (22%)
• Similarity: 183/476 - (38%)
• Gaps: 139/476 - (29%)

  Fly   177 PTLVLDREVASINVPANAKAIIAEQGPSTYSKEALIKDKLKPDPSTLVEIEKSLLSLFNMKRPPK 241
            ||...:...|:.:.|:.|.|.:.:.||::             .|..:..::|.:|::.::|:.|.
  Rat    22 PTPGSEGHGAAPDCPSCALATLPKDGPNS-------------QPEMVEAVKKHILNMLHLKKRPD 73

  Fly   242 IDR--SKIIIPEPMKKLYAEIMGH------ELDSVNIPKPGLLTKSANTVRSFTHKDSKIDDRFP 298
            :.:  .|..:...::||:...:|.      |.|.....:...|.:..:.:.:|....:.
  Rat    74 VTQPVPKAALLNAIRKLHVGKVGENGYVEIEDDIGRRAEMNELMEQTSEIITFAESGTA------ 132

  Fly   299 HHHRFRLHFDVKSIPAD-EKLKAAELQLTRDALSQQVVASRSSANRTRYQVLVY----------- 351
               |..|||::....:| ..::.||:.|         ......|||||.:|.:.
  Rat   133 ---RKTLHFEISKEGSDLSVVERAEVWL---------FLKVPKANRTRTKVTIRLFQQQKHPQGS 185

  Fly   352 -----DITRVGVRGQREPSYLLLDTKTVRLNSTD----TVSLDVQPAVDRWLASPQRNYGLLVEV 407
                 :...:|::|:|  |.|||..|.|....:.    .||..:|..:|:..:|        ::|
  Rat   186 LDMGDEAEEMGLKGER--SELLLSEKVVDARKSTWHIFPVSSSIQRLLDQGKSS--------LDV 240

  Fly   408 RTVRSLKPAPHHHVRLRRSADEAHERWQHKQPLLFTYTDDGRHKARSIRDVSGGEGGGKGG--RN 470
            |.                    |.|:.|.....|...   |:.|.:.:......:.|..||  ..
  Rat   241 RI--------------------ACEQCQESGASLVLL---GKKKKKEVDGDGKKKDGSDGGLEEE 282

  Fly   471 KRQPRRP----TRRKNHD----------------DTCRRHSLYVDFSDVGWDDWIVAPLGYDAYY 515
            |.|..||    ..|::.|                :.|.:...:|.|.|:||:|||:||.||.|.|
  Rat   283 KEQSHRPFLMLQARQSEDHPHRRRRRGLECDGKVNICCKKQFFVSFKDIGWNDWIIAPSGYHANY 347

  Fly   516 CHGKCPFPLA--------------DHFNSTNHAVVQTLVNNMNPGKVPKACCVPTQLDSVAMLYL 566
            |.|:||..:|              :|:....|:....|          |:|||||:|..::|||.
  Rat   348 CEGECPSHIAGTSGSSLSFHSTVINHYRMRGHSPFANL----------KSCCVPTKLRPMSMLYY 402

  Fly   567 NDQSTVVLKNYQEMTVVGCGC 587
            :|...::.|:.|.|.|..|||
  Rat   403 DDGQNIIKKDIQNMIVEECGC 423

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dpp	NP_477311.1	TGFb_propeptide	225..444	CDD:279078	46/247 (19%)
		TGFB	487..588	CDD:214556	41/115 (36%)
Inhba	NP_058824.1	TGFb_propeptide	56..236	CDD:413528	39/199 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	264..306		9/41 (22%)
		TGF_beta_INHBA	317..424	CDD:381674	41/117 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3900
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810