Protein Alignment dpp and Lefty2

DIOPT Version :9

• Sequence 1: NP_477311.1
• Gene: dpp / 33432
• FlyBaseID: FBgn0000490
• Length: 588
• Species: Drosophila melanogaster
• Sequence 2: NP_001007557.1
• Gene: Lefty2 / 289316
• RGDID: 1359679
• Length: 366
• Species: Rattus norvegicus
• Alignment Length: 407
• Identity: 79/407 - (19%)
• Similarity: 138/407 - (33%)
• Gaps: 123/407 - (30%)

  Fly   225 EIEKSLLSLFNMKRPPKIDRSKI---IIPEPMKKLYAEIMGHELDSVNIPKPGLLTKSANTVRSF 286
            ::..|||....:.:.|.:||..:   .||..:...|..::                       ..
  Rat    26 QVLSSLLKQLQLSQAPVLDRVDVEGMAIPTHVSSQYVALL-----------------------QG 67

  Fly   287 THKDSKIDDRFPHHHR-------------FRLHFDVKS-IPADEKLKAAELQLTRDALSQQVV-- 335
            :|.|.....||..:.|             ..|.|.::. :|.:.:|..|.|:|.::.:.:..:
  Rat    68 SHADRSRGKRFSQNFREVAGRFLVSETSSHLLVFGMEQRLPPNSELVQAMLRLFQEPVPRTALRR 132

  Fly   336 ASRSSANRTRYQVLVYDITRVGVRGQREPSYLLLDTKTVRLNSTDTVSLDVQPAVDRWLASPQRN 400
            ..|...:..:.:|.: :..||...|....:  |:|::.|.:..:.....||..||:.|....:..
  Rat   133 LERLPPHSAQARVTI-EWLRVREDGSNRTA--LIDSRLVSIYESGWKVFDVTEAVNFWQQLSRPR 194

  Fly   401 YGLLVEVRTVRS-LKPAPHHHVRLRRSADEAHERWQHKQPLLFTYTDDGRHKAR------SIRDV 458
            ..||::|...|. |.|......:|.|.|.:.              |.||:.:.:      .::|.
  Rat   195 QPLLLQVSVQREHLGPGTWSAHKLVRFAAQG--------------TPDGKGEPQLELHTLDLKDY 245

  Fly   459 SGGEGGGKGGRNKRQPRRPTRRKNHDDTCRRHSLYVDFSDVGW-DDWIVAPLGYDAYYCHGKC-- 520
                    |.:....|..|.   .....|.|..:|:|...:.| ::||:.|.|:..|.|.|.|
  Rat   246 --------GAQGNCDPEAPV---TEGTRCCRKEMYLDLQGMKWAENWILEPPGFLIYECVGSCRQ 299

  Fly   521 ---------PFPLADHFNSTNHAVVQTLVNNMNPGKVPKACCVPTQLDSVAML--YLNDQST--- 571
                     ||                    :.|.:     ||.:::.|:.|:  ...|..|
  Rat   300 LPESLTIGWPF--------------------LGPRQ-----CVASEMTSLPMIVSIKEDGKTRPQ 339

  Fly   572 -VVLKNYQEMTVVGCGC 587
             |.|.|   |.|..|.|
  Rat   340 VVSLPN---MRVQTCSC 353

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dpp	NP_477311.1	TGFb_propeptide	225..444	CDD:279078	43/238 (18%)
		TGFB	487..588	CDD:214556	29/119 (24%)
Lefty2	NP_001007557.1	TGF-beta propeptide	45..231		41/225 (18%)
		TGFb_propeptide	<68..211	CDD:279078	30/145 (21%)
		TGF_beta	261..353	CDD:278448	28/119 (24%)
		transforming growth factor beta-like domain	263..353		28/117 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910