Protein Alignment dpp and Tgfb3

DIOPT Version :9

• Sequence 1: NP_477311.1
• Gene: dpp / 33432
• FlyBaseID: FBgn0000490
• Length: 588
• Species: Drosophila melanogaster
• Sequence 2: NP_037306.1
• Gene: Tgfb3 / 25717
• RGDID: 3851
• Length: 412
• Species: Rattus norvegicus
• Alignment Length: 410
• Identity: 103/410 - (25%)
• Similarity: 159/410 - (38%)
• Gaps: 79/410 - (19%)

  Fly   212 IKDKLK----PDPSTLVEIEKSLLSLFNMKR----PPKIDRSKIIIPEPMKKLYAEIMGHELDSV 268
            |..||:    |:||.:..:...:|:|:|..|    ....:|.:....|..:..|.....|:.|.:
  Rat    47 ILSKLRLTSPPEPSVMTHVPYQVLALYNSTRELLEEMHGEREEGCTQETSESEYYAKEIHKFDMI 111

  Fly   269 NIPKPGLLTKSANTV--RSFTHKDSKIDDRFPHHHRFRLHFDVKSIPAD-EKLKAAELQLTRDAL 330
            .    ||...:...|  :..|   ||:         ||  |:|.|:..: ..|..||.::.|
  Rat   112 Q----GLAEHNELAVCPKGIT---SKV---------FR--FNVSSVEKNGTNLFRAEFRVLR--- 155

  Fly   331 SQQVVASRSSANRTRYQVLVYDITRVG--VRGQREPSYLLLDTKTVRLNSTDTVSLDVQPAVDRW 393
                 ....|:.||..::.::.|.|..  :..||......|.|:    .:.:.:|.||...|..|
  Rat   156 -----VPNPSSKRTEQRIELFQILRPDEHIAKQRYIGGKNLPTR----GTAEWLSFDVTDTVREW 211

  Fly   394 LASPQRNYGLLVEVRTVRSLKPAPHHHVRLRRS-ADEAHERWQHKQPLLFTYTDDGR-------- 449
            |...:.|.||.:.:.       .|.|..:.... .:..||..:.|...:....|.||
  Rat   212 LLRRESNLGLEISIH-------CPCHTFQPNGDILENVHEVMEIKFKGVDNEDDHGRGDLGRLKK 269

  Fly   450 ----HKARSI-------RDVSGGEGGGKGGRNKRQPRRPTRRKNHDDTCRRHSLYVDF-SDVGWD 502
                |....|       |..|.|:|   |.|.||........:|.::.|....||:|| .|:||
  Rat   270 QKDHHNPHLILMMIPPHRLDSPGQG---GQRKKRALDTNYCFRNLEENCCVRPLYIDFRQDLGW- 330

  Fly   503 DWIVAPLGYDAYYCHGKCPFPLADHFNSTNHAVVQTLVNNMNPGKVPKACCVPTQLDSVAMLYLN 567
            .|:..|.||.|.:|.|.||:..:   :.|.|:.|..|.|.:||......||||..|:.:.:||..
  Rat   331 KWVHEPKGYYANFCSGPCPYLRS---SDTTHSTVLGLYNTLNPEASASPCCVPQDLEPLTILYYV 392

  Fly   568 DQSTVVLKNYQEMTVVGCGC 587
            .: |..::....|.|..|.|
  Rat   393 GR-TPKVEQLSNMVVKSCKC 411

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dpp	NP_477311.1	TGFb_propeptide	225..444	CDD:279078	47/228 (21%)
		TGFB	487..588	CDD:214556	36/102 (35%)
Tgfb3	NP_037306.1	TGFb_propeptide	24..230	CDD:395559	49/219 (22%)
		Cell attachment site. /evidence=ECO:0000250|UniProtKB:P01137	261..263		1/1 (100%)
		TGF_beta_TGFB3	312..412	CDD:381656	36/105 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3900
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810