Protein Alignment dpp and Bmp3

DIOPT Version :9

• Sequence 1: NP_477311.1
• Gene: dpp / 33432
• FlyBaseID: FBgn0000490
• Length: 588
• Species: Drosophila melanogaster
• Sequence 2: NP_058801.1
• Gene: Bmp3 / 25667
• RGDID: 2212
• Length: 468
• Species: Rattus norvegicus
• Alignment Length: 574
• Identity: 129/574 - (22%)
• Similarity: 199/574 - (34%)
• Gaps: 207/574 - (36%)

  Fly    49 SGSGRS-GSRSVGASTSTALAKAFNPFSEPASFSDSDKSHRSKTNKKPSKSDANRQFNEVHKPRT 112
            |||.|: .:|:.|:..         |..:|....::.:|.|       :.:....|...:|....
  Rat    68 SGSNRAQATRTPGSQL---------PGPQPLRGGNTVRSFR-------AAAAGTLQRKGLHTFNL 116

  Fly   113 DQLENSKN-KSKQL-----------VNKPNHNKMAVKEQRSHHKKSHHHRSHQPKQASASTESHQ 165
            ..|..|:| .|..|           ||.|.....:...||.|         .|...::.:.:|:|
  Rat   117 TSLTKSENILSATLYFYIGELVNTSVNCPESQGCSHDSQRQH---------IQIDLSAWTLQSNQ 172

  Fly   166 SSSIESIFVEEPTLVLDREVASINVPANAKAIIAEQGPSTYSKEALIKD------KLKPDPSTLV 224
            |..:..:.|:                 .||       |...|...|.||      |.|.|...|:
  Rat   173 SQLLGHLSVD-----------------TAK-------PYRDSMSWLSKDITQLLRKAKQDEEFLI 213

  Fly   225 EIEKSLLSLFNM-KRPPKIDRSKIIIPEPMKKLYAEIMGHELDSVNIPKPGLLTKSANTVRSFTH 288
            .        ||: .|..::.:..::.|||...:||       :...|.:|..:..|....|.||
  Rat   214 G--------FNITSRAHELPKRMLLFPEPYILVYA-------NDAAICEPESVVSSLQRHRDFT- 262

  Fly   289 KDSKIDDRFPHHHRFRLHFDVKSIPADEKLKAAELQLTRDALSQQVVASRSSANRTRYQVLV--- 350
              :....|...|                         .|:|||.:....||:.      :|:
  Rat   263 --AGTVPRLDSH-------------------------VREALSVERRKKRSTG------ILLPLQ 294

  Fly   351 --------YDITRVGVRGQREPSYLLLDTKTVRLNSTDTVSLDVQPAVDRWLASPQRNYGLLVEV 407
                    |.....||..:|:|                ..||..||        |:::
  Rat   295 NNELPGAEYQYKEAGVWEERKP----------------YKSLQTQP--------PEKS------- 328

  Fly   408 RTVRSLKPAPHHHVRLRRSADEAHERWQHKQPLLFTYTDDGRHKARSIRDVSGGEGGGKGGRNKR 472
            |:.:..:..||                |..|.|.|                  .|...|..|.|:
  Rat   329 RSKKKQRKGPH----------------QKGQTLQF------------------DEQTLKKARRKQ 359

  Fly   473 --QPRRPTRRKNHDDTCRRHSLYVDFSDVGWDDWIVAPLGYDAYYCHGKCPFPLADHFNSTNHAV 535
              :||          .|.|..|.|||:|:||.:||::|..:|||||.|.|.||:......:|||.
  Rat   360 WIEPR----------NCARRYLKVDFADIGWSEWIISPKSFDAYYCSGACQFPMPKSLKPSNHAT 414

  Fly   536 VQTLVNNMN-PGKVPKACCVPTQLDSVAMLYLNDQSTVVLKNYQEMTVVGCGCR 588
            :|::|..:. ...:|:.||||.::.|:::|:.::...||||.|..|||..|.||
  Rat   415 IQSIVRAVGVVSGIPEPCCVPEKMSSLSILFFDENKNVVLKVYPNMTVDSCACR 468

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dpp	NP_477311.1	TGFb_propeptide	225..444	CDD:279078	40/230 (17%)
		TGFB	487..588	CDD:214556	42/101 (42%)
Bmp3	NP_058801.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	27..53
		TGFb_propeptide	46..>203	CDD:279078	35/183 (19%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	72..93		5/29 (17%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	316..349		13/97 (13%)
		TGF_beta	364..467	CDD:278448	43/112 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3900
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810