Protein Alignment dpp and Gdf15

DIOPT Version :9

• Sequence 1: NP_477311.1
• Gene: dpp / 33432
• FlyBaseID: FBgn0000490
• Length: 588
• Species: Drosophila melanogaster
• Sequence 2: NP_001317616.1
• Gene: Gdf15 / 23886
• MGIID: 1346047
• Length: 303
• Species: Mus musculus
• Alignment Length: 319
• Identity: 80/319 - (25%)
• Similarity: 123/319 - (38%)
• Gaps: 91/319 - (28%)

  Fly   308 DVKSIPADEKLKAAELQLTRDALSQQVVASRSSANRTRYQVLVYDITRVGVRGQREPSYLLLDTK 372
            |..::| :::....|.||..|.|            |.|:|.|   ::|:.....||.|
Mouse    36 DALAMP-EQRPSGPESQLNADEL------------RGRFQDL---LSRLHANQSREDS------- 77

  Fly   373 TVRLNSTDTVSLDVQPAVDRWLASPQRNYG----LLVEVRTVRSLKPAPHHHVRLRRSADEAHER 433
                ||..:    ..|||.  :.||:...|    ||:.|           :...|.:...||:.
Mouse    78 ----NSEPS----PDPAVR--ILSPEVRLGSHGQLLLRV-----------NRASLSQGLPEAYR- 120

  Fly   434 WQHKQPLLFTYT----DDGR--HKARSIR---------------DV----SGGE--------GGG 465
             .|:..||.|.|    |..|  .:|.|:|               |:    |||.        ..|
Mouse   121 -VHRALLLLTPTARPWDITRPLKRALSLRGPRAPALRLRLTPPPDLAMLPSGGTQLELRLRVAAG 184

  Fly   466 KGGRNKRQPRRPTRRKNHDDTCRRHSLYVDFSDVGWDDWIVAPLGYDAYYCHGKCPFPLADH-FN 529
            :|.|:.....|.:........|...::.....|:||.||:::|.......|.|:||     | :.
Mouse   185 RGRRSAHAHPRDSCPLGPGRCCHLETVQATLEDLGWSDWVLSPRQLQLSMCVGECP-----HLYR 244

  Fly   530 STN-HAVVQTLVNNMNPGKVPKACCVPTQLDSVAMLYLNDQSTVVLKNYQEMTVVGCGC 587
            |.| ||.::..::.:.|.|||..||||:....|.:::..| |.|.|:.|.::...||.|
Mouse   245 SANTHAQIKARLHGLQPDKVPAPCCVPSSYTPVVLMHRTD-SGVSLQTYDDLVARGCHC 302

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dpp	NP_477311.1	TGFb_propeptide	225..444	CDD:279078	32/139 (23%)
		TGFB	487..588	CDD:214556	33/103 (32%)
Gdf15	NP_001317616.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3900
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810