Protein Alignment dpp and Gdf7

DIOPT Version :9

• Sequence 1: NP_477311.1
• Gene: dpp / 33432
• FlyBaseID: FBgn0000490
• Length: 588
• Species: Drosophila melanogaster
• Sequence 2: NP_001299805.1
• Gene: Gdf7 / 238057
• MGIID: 95690
• Length: 461
• Species: Mus musculus
• Alignment Length: 460
• Identity: 122/460 - (26%)
• Similarity: 184/460 - (40%)
• Gaps: 125/460 - (27%)

  Fly   202 GPSTYSKEALIKDKLKPDPSTLVEIEKSLLSLFNMKRPPKIDRSKIIIPEP-MKKLYAEIMGHEL 265
            |||.....|:      |.|..   :.::..|.|         |:..::|.. |..||..:.|.
Mouse    54 GPSALQAAAV------PGPRA---VRRAAGSGF---------RNGSVVPHHFMMSLYRSLAGR-- 98

  Fly   266 DSVNIPKPGLLTKS---ANTVRSFTHKDSKIDDRFPHHHRFRLHFDVKSIPADEKLKAAELQLTR 327
                  .|......   .:|:..||.:.:: |:...........|||.|:...:::..|||::.|
Mouse    99 ------APVAAASGHGRVDTITGFTDQATQ-DETAAAEPGQSFLFDVSSLSEADEVVNAELRVLR 156

  Fly   328 DALSQQVVASRSSANRTRYQVLVYDITRVGVRGQREPSYLLLDTKTVRLNSTDTVSLDVQPAVD- 391
               .:.....|.||......:|.......|.      ::||.......|......:.||..||.
Mouse   157 ---RRSPEPDRDSATLLPRLLLSTCPDEAGT------AHLLHSRAAEPLGGARWEAFDVTDAVQS 212

  Fly   392 --RWLASPQRNYGLLVEVRTVRSLKPAPHHHVRLRR--------------SADE-----AHERWQ 435
              ||   |:.:....:.:|.|.:.:.:|   :.|||              :|:|     ...|.|
Mouse   213 HRRW---PRASRKFCLVLRAVTASESSP---LALRRLGFGWPGGGDGGGTAAEERALLVISSRTQ 271

  Fly   436 HKQPLLFTYTDDGRHKARSIRDVS----------------------------------------- 459
            .|:.|.    .:.|.:||::|..:
Mouse   272 RKESLF----REIRAQARALRAAAEPPPDPGPGAGSRKANLGGRRRRRTALAGTRGAQGSGGGGG 332

  Fly   460 ------GGEGGGKGGRNKRQPRRPTRRKNHDDTCRRHSLYVDFSDVGWDDWIVAPLGYDAYYCHG 518
                  ||.|||.||..:...||...|      |.|.||:|||.::||||||:|||.|:||:|.|
Mouse   333 GGGGGGGGGGGGGGGAGRGHGRRGRSR------CSRKSLHVDFKELGWDDWIIAPLDYEAYHCEG 391

  Fly   519 KCPFPLADHFNSTNHAVVQTLVNNMNPGKVPKACCVPTQLDSVAMLYLNDQSTVVLKNYQEMTVV 583
            .|.|||..|...||||::|||:|:|.|...|.:||||.:|..:::||::..:.||.|.|::|.|.
Mouse   392 VCDFPLRSHLEPTNHAIIQTLLNSMAPDAAPASCCVPARLSPISILYIDAANNVVYKQYEDMVVE 456

  Fly   584 GCGCR 588
            .||||
Mouse   457 ACGCR 461

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dpp	NP_477311.1	TGFb_propeptide	225..444	CDD:279078	48/244 (20%)
		TGFB	487..588	CDD:214556	52/100 (52%)
Gdf7	NP_001299805.1	TGFb_propeptide	<87..232	CDD:279078	34/165 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	287..360		11/78 (14%)
		TGFB	363..461	CDD:214556	50/97 (52%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3900
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810