Protein Alignment dpp and Tgfb3

DIOPT Version :9

• Sequence 1: NP_477311.1
• Gene: dpp / 33432
• FlyBaseID: FBgn0000490
• Length: 588
• Species: Drosophila melanogaster
• Sequence 2: NP_033394.2
• Gene: Tgfb3 / 21809
• MGIID: 98727
• Length: 412
• Species: Mus musculus
• Alignment Length: 431
• Identity: 103/431 - (23%)
• Similarity: 159/431 - (36%)
• Gaps: 121/431 - (28%)

  Fly   212 IKDKLK----PDPSTLVEIEKSLLSLFNMKR----PPKIDRSKIIIPEPMKKLYAEIMGHELDSV 268
            |..||:    |:||.:..:...:|:|:|..|    ....:|.:....|..:..|.....|:.|.:
Mouse    47 ILSKLRLTSPPEPSVMTHVPYQVLALYNSTRELLEEMHGEREEGCTQETSESEYYAKEIHKFDMI 111

  Fly   269 NIPKPGLLTKSANTV--RSFTHKDSKIDDRFPHHHRFRLHFDVKSIPAD-EKLKAAELQLTRDAL 330
            .    ||...:...|  :..|   ||:         ||  |:|.|:..: ..|..||.::.|
Mouse   112 Q----GLAEHNELAVCPKGIT---SKV---------FR--FNVSSVEKNGTNLFRAEFRVLR--- 155

  Fly   331 SQQVVASRSSANRTRYQVLVYDITRVG--VRGQREPSYLLLDTKTVRLNSTDTVSLDVQPAVDRW 393
                 ....|:.||..::.::.|.|..  :..||......|.|:    .:.:.:|.||...|..|
Mouse   156 -----VPNPSSKRTEQRIELFQILRPDEHIAKQRYIGGKNLPTR----GTAEWLSFDVTDTVREW 211

  Fly   394 LASPQRNYGLLVEVRTVRSLKPAPHHHVRLRRSADEAHERWQHKQPLLFTYTDDGR-----HKAR 453
            |...:.|.||.:.:.       .|.|                       |:..:|.     |:..
Mouse   212 LLRRESNLGLEISIH-------CPCH-----------------------TFQPNGDILENVHEVM 246

  Fly   454 SIR----DVSGGEGGGKGGRNKRQ--------------------PRRPTRRK-----------NH 483
            .|:    |.....|.|..||.|:|                    |.:.::||           |.
Mouse   247 EIKFKGVDNEDDHGRGDLGRLKKQKDHHNPHLILMMIPPHRLDSPGQGSQRKKRALDTNYCFRNL 311

  Fly   484 DDTCRRHSLYVDF-SDVGWDDWIVAPLGYDAYYCHGKCPF-PLADHFNSTNHAVVQTLVNNMNPG 546
            ::.|....||:|| .|:|| .|:..|.||.|.:|.|.||: ..||    |.|:.|..|.|.:||.
Mouse   312 EENCCVRPLYIDFRQDLGW-KWVHEPKGYYANFCSGPCPYLRSAD----TTHSTVLGLYNTLNPE 371

  Fly   547 KVPKACCVPTQLDSVAMLYLNDQSTVVLKNYQEMTVVGCGC 587
            .....||||..|:.:.:||...: |..::....|.|..|.|
Mouse   372 ASASPCCVPQDLEPLTILYYVGR-TPKVEQLSNMVVKSCKC 411

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dpp	NP_477311.1	TGFb_propeptide	225..444	CDD:279078	44/227 (19%)
		TGFB	487..588	CDD:214556	38/103 (37%)
Tgfb3	NP_033394.2	TGFb_propeptide	24..230	CDD:366248	49/219 (22%)
		TGF_beta_TGFB3	312..412	CDD:381656	38/106 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3900
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810