Protein Alignment dpp and Tgfb2

DIOPT Version :9

• Sequence 1: NP_477311.1
• Gene: dpp / 33432
• FlyBaseID: FBgn0000490
• Length: 588
• Species: Drosophila melanogaster
• Sequence 2: NP_001316036.1
• Gene: Tgfb2 / 21808
• MGIID: 98726
• Length: 442
• Species: Mus musculus
• Alignment Length: 427
• Identity: 106/427 - (24%)
• Similarity: 171/427 - (40%)
• Gaps: 80/427 - (18%)

  Fly   212 IKDKLK--------PDPSTLVEIEKSLLSLFN----------MKRPPKIDRSKIIIPEPMKKLYA 258
            |..|||        |:|.   |:...::|::|          .:|....:|.:.......|::|.
Mouse    44 ILSKLKLTSPPEDYPEPD---EVPPEVISIYNSTRDLLQEKASRRAAACERERSDEEYYAKEVYK 105

  Fly   259 EIMGHELDSVNI-PKPGLLTKSANTVRSFTHKDSKI-----DDRFPHHHR--FRL-HFDVKSIPA 314
            ..|...|.|..: |   ::|..:.::.||..:.|::     |...|..:|  ||: .|||.::..
Mouse   106 IDMPSHLPSETVCP---VVTTPSGSLGSFCSRQSQVLCGYLDAIPPTFYRPYFRIVRFDVSTMEK 167

  Fly   315 D-EKLKAAELQLTRDALSQQVVASRSSANRTR-YQVL-VYDITRVGVRGQREPSYLLLDTKTVRL 376
            : ..|..||.::.|    .|...:|.:..|.. ||:| ..|:|        .|:...:|:|.|:.
Mouse   168 NASNLVKAEFRVFR----LQNPKARVAEQRIELYQILKSKDLT--------SPTQRYIDSKVVKT 220

  Fly   377 NST-DTVSLDVQPAVDRWLASPQRNYGLLVEVRTVRSLKP----APHHHVRLRRSADEAHERWQH 436
            .:. :.:|.||..||..||....||.|..:.:..     |    .|.::..:...::|...|:..
Mouse   221 RAEGEWLSFDVTDAVQEWLHHKDRNLGFKISLHC-----PCCTFVPSNNYIIPNKSEELEARFAG 280

  Fly   437 KQPLLFTYTDDGRHKARSIRDVSGG---------------EGGGKGGRNKRQPRRPTRRKNHDDT 486
            ... ..||....:...:|.|..:.|               |......|.||........:|..|.
Mouse   281 IDG-TSTYASGDQKTIKSTRKKTSGKTPHLLLMLLPSYRLESQQSSRRKKRALDAAYCFRNVQDN 344

  Fly   487 CRRHSLYVDFS-DVGWDDWIVAPLGYDAYYCHGKCPFPLADHFNSTNHAVVQTLVNNMNPGKVPK 550
            |....||:||. |:|| .||..|.||:|.:|.|.||:..:   :.|.|..|.:|.|.:||.....
Mouse   345 CCLRPLYIDFKRDLGW-KWIHEPKGYNANFCAGACPYLWS---SDTQHTKVLSLYNTINPEASAS 405

  Fly   551 ACCVPTQLDSVAMLYLNDQSTVVLKNYQEMTVVGCGC 587
            .|||...|:.:.:||... :|..::....|.|..|.|
Mouse   406 PCCVSQDLEPLTILYYIG-NTPKIEQLSNMIVKSCKC 441

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dpp	NP_477311.1	TGFb_propeptide	225..444	CDD:279078	53/245 (22%)
		TGFB	487..588	CDD:214556	36/102 (35%)
Tgfb2	NP_001316036.1	TGFb_propeptide	21..256	CDD:279078	55/234 (24%)
		TGF_beta	344..441	CDD:278448	35/101 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3900
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810