Protein Alignment dpp and Nodal

DIOPT Version :9

• Sequence 1: NP_477311.1
• Gene: dpp / 33432
• FlyBaseID: FBgn0000490
• Length: 588
• Species: Drosophila melanogaster
• Sequence 2: NP_038639.2
• Gene: Nodal / 18119
• MGIID: 97359
• Length: 354
• Species: Mus musculus
• Alignment Length: 396
• Identity: 98/396 - (24%)
• Similarity: 153/396 - (38%)
• Gaps: 139/396 - (35%)

  Fly   250 PEP---MKKLYAEIMGHELDSVNIPKPGLLTKSANTVRSFTHKDSKIDDRFPHHHRFRLHFDVKS 311
            |.|   |..||.:           |.|     .|:.:||...:|..:..:     .:...||...
Mouse    39 PSPLAYMLSLYRD-----------PLP-----RADIIRSLQAQDVDVTGQ-----NWTFTFDFSF 82

  Fly   312 IPADEKLKAAELQ--------------LTRDALSQQVVASRSSANRTRYQVLVYDITRVGVRG-- 360
            :..:|.|..|||:              ||.|...|                         .:|
Mouse    83 LSQEEDLVWAELRLQLPGPMDIPTEGPLTIDIFHQ-------------------------AKGDP 122

  Fly   361 QREPSYLL----LDTKT-----VRLNSTDTVSLDVQPAVDRWLASPQRNYGLLVEVRTVRSLKPA 416
            :|:|:..|    ::|.|     |...|..|| |:|...:.:||..|             |:|:
Mouse   123 ERDPADCLERIWMETFTVIPSQVTFASGSTV-LEVTKPLSKWLKDP-------------RALE-- 171

  Fly   417 PHHHVRLRRSADEAHERWQHKQP-----------LLFTYTDDGRHKARSIRDVSGG--------- 461
                   ::.:..|.:.|.  ||           :|..|:    ::.:..|.:.|.
Mouse   172 -------KQVSSRAEKCWH--QPYTPPVPVASTNVLMLYS----NRPQEQRQLGGATLLWEAESS 223

  Fly   462 ----------EGGGKGGRNKRQPRRPTRRKNHDDTCRRHSLYVDFSDVGWDDWIVAPLGYDAYYC 516
                      |.|| .||.:|:...|.|    ...|||....|||:.:||..||:.|..|:||.|
Mouse   224 WRAQEGQLSVERGG-WGRRQRRHHLPDR----SQLCRRVKFQVDFNLIGWGSWIIYPKQYNAYRC 283

  Fly   517 HGKCPFPLADHFNSTNHAVVQTLVNNMNPGKVPKACCVPTQLDSVAMLYLNDQSTVVLKNYQEMT 581
            .|:||.|:.:.|:.||||.:|:|:....|.:||..||.|.:...::|||: |...|:|:::::|.
Mouse   284 EGECPNPVGEEFHPTNHAYIQSLLKRYQPHRVPSTCCAPVKTKPLSMLYV-DNGRVLLEHHKDMI 347

  Fly   582 VVGCGC 587
            |..|||
Mouse   348 VEECGC 353

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dpp	NP_477311.1	TGFb_propeptide	225..444	CDD:279078	44/232 (19%)
		TGFB	487..588	CDD:214556	43/101 (43%)
Nodal	NP_038639.2	TGFb_propeptide	33..169	CDD:279078	37/189 (20%)
		TGFB	254..353	CDD:214556	41/99 (41%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3900
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810