Protein Alignment dpp and unc-129

DIOPT Version :9

• Sequence 1: NP_477311.1
• Gene: dpp / 33432
• FlyBaseID: FBgn0000490
• Length: 588
• Species: Drosophila melanogaster
• Sequence 2: NP_501566.1
• Gene: unc-129 / 177719
• WormBaseID: WBGene00006852
• Length: 407
• Species: Caenorhabditis elegans
• Alignment Length: 433
• Identity: 100/433 - (23%)
• Similarity: 158/433 - (36%)
• Gaps: 110/433 - (25%)

  Fly   230 LLSLFNMKRPPKID-------------------------RSKIIIPEPMKKLYAEIMGHELDSVN 269
            |||:|::....|:|                         ||...:.|.||.||...:..:.:
 Worm     9 LLSVFSIANCAKVDVDLINETIRDLLHFKSSDPNVTSFHRSSHTLTEHMKNLYENFIDEDSN--- 70

  Fly   270 IPKPGLLTKSANTVRSFTHKDSKIDDRFPHHHRFRLHFDVKSIPADEKLKAAELQL---TRDAL- 330
                    :..|.||:......|.:.:..      |.|||:...:.|.:..|||..   .||:.
 Worm    71 --------EDGNLVRAIEPAVGKFEGQEV------LVFDVEGFDSHESIMRAELHFYLRRRDSFA 121

  Fly   331 ---SQQVVASRSSANRTRYQVLVYDITRVGVRGQREPSYLLLD-TKTVRLNSTDTVSLDVQPAVD 391
               |:|:.|.....|....|..:..| |||.....|...::.| ||:|    .|:..||.:.||.
 Worm   122 RRRSRQIRAKSVCVNEYCRQQTLKKI-RVGGDENLEEYKVIWDATKSV----FDSYHLDAKQAVF 181

  Fly   392 RWLA--SPQRNYGLLVE---------------VRTVRSLKPAPHHHVRLRRSA--DEAHERWQHK 437
            |...  |..|.|..::.               :.||..:|.. ....|.||..  :|..|.:.:.
 Worm   182 RITREHSKMRPYAEMIRKSTPFLVIYSKVNHTLDTVSVMKQT-EQTKRKRRDLGNEELREYYNYN 245

  Fly   438 Q-PLLFTYTDDGRH-------KARSIRDVSGGEG--GGKGGRNKRQPRRPTRRKNHD-------- 484
            . ||    .:|.|.       |..|:.:....|.  .|.|....|:.|.  |..|.:
 Worm   246 SIPL----DNDDREPIKRKNGKKNSLSEEISSEDVWQGFGEETSREERE--RIANEELANDVRVV 304

  Fly   485 -----DTCRRHSLYVDFSDVGWDDWIVAPLGYDAYYCHGKCPFPLADHFNSTNHAVVQTLVNNMN 544
                 :.|.:..:.|.....|||.:::.|...:..:|.|||..|:.....::|||::|:|.
 Worm   305 LLQNKNRCHKEGVLVSLKHFGWDRYVIEPKTIETSFCKGKCAKPMLTSGKASNHAMLQSLF---- 365

  Fly   545 PGKVPKACCVPTQLDSVAMLYLNDQSTVVLKNYQEMTVVGCGC 587
              .....||.||.|.|:...|.:::...|::||.:|.:..|.|
 Worm   366 --AAEPVCCAPTNLKSLNFWYRDEKGRTVIRNYSKMLIGSCSC 406

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dpp	NP_477311.1	TGFb_propeptide	225..444	CDD:279078	60/266 (23%)
		TGFB	487..588	CDD:214556	29/101 (29%)
unc-129	NP_501566.1	TGFB	312..406	CDD:214556	28/99 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3900
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810